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Updated: Apr 12, 2026

Methods for Detecting Cough and Airway Inflammation in Mice
Published on: August 2, 2024
Neurogenic Cough
Bryan Renslo1, Kathleen M Tibbetts1
1Department of Otolaryngology-Head and Neck Surgery, Thomas Jefferson University Hospital, 925 Chestnut Street 6th Floor, Philadelphia, PA 19107, USA.
None:
Neurogenic cough is a diagnosis of exclusion characterized by laryngeal hypersensitivity. More common etiologies of chronic cough should be systematically excluded prior to diagnosis. Although the pathophysiology of neurogenic cough is not fully understood, proposed etiologies typically involve injury to the vagus nerve. Treatment options include neuromodulating medications, behavioral cough suppression therapy, and procedures such as superior laryngeal nerve block. Newer targeted treatments, including P2X3 antagonists, may offer effective treatment alternatives moving forward.
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