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Updated: Apr 12, 2026

Hybrid De Novo Genome Assembly for the Generation of Complete Genomes of Urinary Bacteria using Short- and Long-read Sequencing Technologies
Published on: August 20, 2021
Chromosome-level genome assembly and annotation of the moon jellyfish Aurelia coerulea
Xinyue Hu1,2,3, Yang Guo4, Ze Zhang5,6,7
1College of Life Sciences, University of Chinese Academy of Sciences, Beijing, 100049, China.
Abstract:
Aurelia coerulea (moon jellyfish), a radially symmetrical metazoan in the phylum Cnidaria, possesses key features pertinent to understanding the evolutionary origins of nervous systems. Here, we employed a combination of long-read sequencing, short-read sequencing, and Hi-C chromatin conformation capture techniques to generate a chromosome-level assembly of the A. coerulea genome. The final assembly comprises approximately 554.10 Mb distributed across 21 chromosomes, achieving a scaffold N50 of 24.06 Mb and demonstrating high completeness (protein BUSCO score: 93.0%). Approximately 71.48% of the genome consists of transposable elements. We identified 26,777 protein-coding genes, of which approximately 72.28% have been functionally annotated. This chromosome-level genome provides an essential resource for elucidating early neural evolution and advancing our understanding of cnidarian biology.
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