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Regression Toward the Mean01:52

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'Boden Food Plate': Novel Interactive Web-based Method for the Assessment of Dietary Intake
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Reliability of Self-Reported Maternal Health and Mother-Infant Outcome Data in Web-Based Questionnaires.

Laure Sillis1,2,3, Laura Van Mechelen4, Marleen M H J van Gelder5

  • 1Department of Pharmaceutical and Pharmacological Sciences, KU Leuven, Leuven, Belgium. laure.sillis@kuleuven.be.

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Summary
This summary is machine-generated.

The BELpREG registry shows reliable self-reported data for pregnancy safety studies. Maternal and infant outcomes largely agree with healthcare professional records, supporting its use.

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Area of Science:

  • Perinatal health research
  • Real-world data (RWD) validation
  • Maternal-fetal medicine

Background:

  • The BELpREG registry collects self-reported data on perinatal medication use and mother-infant outcomes in Belgium.
  • Reliable self-reported data is crucial for pregnancy safety studies.
  • Assessing data accuracy in registries is vital for evidence generation.

Purpose of the Study:

  • To evaluate the reliability of maternal health and mother-infant outcome data within the BELpREG registry.
  • To compare self-reported data against medical records from healthcare professionals (HCPs).

Main Methods:

  • Compared self-reported data in BELpREG with medical records from gynaecologists, general practitioners, and midwives.
  • Included 175 pregnant women aged 18+ who delivered between Nov 2022-Apr 2024.
  • Utilized intraclass correlation coefficients (ICCs) for continuous variables (e.g., BMI, gestational age) and Cohen's Kappa for categorical variables (e.g., complications, delivery mode).

Main Results:

  • High reliability was found for pregnancy complications, onset, and delivery mode.
  • Gestational age (ICC 0.99) and infant outcomes (ICC > 0.90) showed excellent concordance.
  • Self-reported maternal BMI had moderate reliability as a continuous measure (ICC 0.75) but high agreement when categorized (Cohen's Kappa 0.89).

Conclusions:

  • The BELpREG registry demonstrates substantial agreement between self-reported and HCP-reported data for key maternal and infant outcomes.
  • These findings support the continued use of the BELpREG registry for pregnancy safety research.
  • High data reliability enhances the value of real-world data in perinatal studies.