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Echovirus type 17 in the neonate.

R S Faulkner, C E Van Rooyen

    Canadian Medical Association Journal
    |April 7, 1973
    PubMed
    Summary

    Echovirus type 17 caused an outbreak in a neonatal nursery, affecting seven infants. While intensive care prevented fatalities in the nursery, another infant died, highlighting the virus's potential severity in neonates.

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    Area of Science:

    • Virology
    • Neonatal Medicine
    • Infectious Diseases

    Background:

    • Echovirus type 17 is a known enterovirus.
    • While typically causing mild illness in adults, its impact on neonates is less understood.

    Purpose of the Study:

    • To document an outbreak of echovirus type 17 in a neonatal intensive care unit.
    • To investigate the clinical presentation and outcomes of echovirus type 17 infection in infants.
    • To report the isolation of echovirus type 17 from postmortem tissues.

    Main Methods:

    • Clinical case description of an echovirus type 17 outbreak in a neonatal nursery.
    • Viral isolation from infant stool and cerebrospinal fluid samples.
    • Autopsy and tissue sample analysis for viral detection in a fatal case.

    Main Results:

    • Seven infants in a neonatal nursery were affected by echovirus type 17, with virus detected in stool and cerebrospinal fluid.
    • Intensive supportive care was crucial in preventing fatalities among the affected infants.
    • A fatal case in another community involved a 5-week-old infant, with echovirus type 17 isolated from multiple organs.

    Conclusions:

    • Echovirus type 17 can cause significant illness in neonates, with a potential for severe outcomes.
    • This study represents the first documented clinical disease outbreak of echovirus type 17 in a neonatal setting.
    • The virus demonstrated an affinity for infant tissues, as evidenced by isolation from postmortem samples.

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