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Updated: Apr 13, 2026

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Strength data for female shield-activated autoinjector users.

Niels Christian Nilsson1, Horacio Bedetti1, Lone Hallum1

  • 1Usability Engineering, Novo Nordisk A/S, Hillerød, Denmark.

Expert Opinion on Drug Delivery
|April 11, 2026
PubMed
Summary
This summary is machine-generated.

Female autoinjector users

Keywords:
Activation forceanthropometric dataautoinjectorgrip typehuman factorsinjection site

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Area of Science:

  • Biomedical Engineering
  • Human Factors Engineering
  • Medical Device Design

Background:

  • Shield-activated autoinjectors are widely used for medication self-administration.
  • Limited data exist on the operational force requirements for these devices.
  • This study addresses the gap by quantifying female users' maximum force capabilities.

Purpose of the Study:

  • To quantify the maximum force capabilities of female autoinjector users.
  • To provide data for optimizing autoinjector design and user training.
  • To inform force specifications for shield-activated autoinjectors.

Main Methods:

  • A study involving 123 female participants across different age groups (young adolescents, adults, elderly).
  • Simulated injections were performed using surrogate autoinjectors to measure activation and hold forces.
  • Variables included age group, grip type (power and precision), and injection site (abdomen, thigh, upper arm).

Main Results:

  • Adults generally exerted higher activation forces compared to other age groups.
  • Power grip consistently yielded higher activation forces than precision grip across all injection sites.
  • Injection site influenced force, with the thigh potentially allowing higher forces with a power grip.

Conclusions:

  • Ecologically valid strength data for female autoinjector users were generated.
  • Findings can inform force specifications for shield-activated autoinjectors.
  • Optimal grip types and injection sites for maximizing force were identified for training purposes.