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Updated: Apr 13, 2026

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Neural implicit heart coordinates: 3D cardiac shape reconstruction from sparse segmentations.

Marica Muffoletto1, Uxio Hermida1, Charlène A Mauger1

  • 1School of Biomedical Engineering and Imaging Sciences, King's College London, London, UK.

Medical Image Analysis
|April 11, 2026
PubMed
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This summary is machine-generated.

Neural Implicit Heart Coordinates (NIHCs) enable accurate 3D cardiac reconstruction from sparse images. This new method provides a standardized anatomical reference frame, improving patient-specific modeling efficiency and accuracy.

Area of Science:

  • Medical Imaging
  • Computational Anatomy
  • Biomedical Engineering

Background:

  • Accurate patient-specific cardiac modeling from limited clinical images is challenging.
  • Existing neural implicit functions have limitations in cross-subject anatomical consistency.
  • Developing standardized anatomical reference frames for the heart is crucial for robust modeling.

Purpose of the Study:

  • Introduce Neural Implicit Heart Coordinates (NIHCs) as a standardized implicit coordinate system for the human heart.
  • Enable anatomically consistent 3D cardiac reconstruction from sparse 2D segmentations.
  • Improve the efficiency and accuracy of patient-specific cardiac modeling.

Main Methods:

  • Developed NIHCs based on universal ventricular coordinates.
Keywords:
3D mesh reconstructionCardiac imagingNeural implicit functionsUniversal ventricular coordinates

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  • Predicted NIHCs directly from sparse 2D cardiac segmentations.
  • Decoded NIHCs into dense 3D segmentations and high-resolution meshes.
  • Trained the model on a large dataset of 5000 cardiac meshes.
  • Main Results:

    • Achieved high reconstruction accuracy with mean Euclidean surface errors of 2.51 ± 0.33 mm (diseased) and 2.31 ± 0.36 mm (healthy).
    • Demonstrated anatomically coherent reconstruction under severe data sparsity and noise.
    • Successfully recovered complex cardiac structures like valve planes.
    • Reduced inference time from over 60s to 5-15s compared to traditional methods.

    Conclusions:

    • NIHCs provide a robust and efficient anatomical representation for 3D cardiac reconstruction.
    • The method significantly improves patient-specific modeling from minimal input data.
    • NIHCs offer a standardized framework for consistent cardiac anatomy mapping across subjects.