Evaluation of senna-based laxatives' candies: A cross-sectional study on constipation management

Constipation is the most common gastrointestinal disorder, significantly imposing a substantial economic burden and impacting quality of life. The prevalence of constipation in Pakistan is 16.1%, indicating increased need of management within the Pakistani population. Therefore, this study aimed to develop a herbal candy and to evaluate the awareness, practices, usage patterns, and sensory perception of laxative for constipation management.

An observational cross-sectional study was conducted from 2024 to 2026. A total of 386 participants were selected for the study to determine the efficacy of laxative candy in relieving constipation. Approval for the study was granted by the Local Research Ethics Committee of the University. However, appropriate statistical tests were used to analyze the data collected.

The study results revealed that 57.4 % of participants took treatment measures for constipation. For one month, 34.6 % used sennative and 59.4 % experienced constipation relief for 3-4 days. For its taste and effectiveness the product was positively rated. A total of 70 % participants found laxative candies more effective than previous treatments. However, 19.9 % participants reported side effects having abdominal pain and cramps. Whereas, 79.8 % reported the product safe. Further, the correlation analysis revealed strong associations laxatives (r = 1.000, p < 0.01), and 74.9 % were willing to recommend the product.

For relieving constipation, sennative observed to be an effective and well-tolerated option. Further, research is needed to evaluate efficacy in broader populations and long-term safety.