Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Psychological and Sociocultural Causes of Schizophrenia01:29

Psychological and Sociocultural Causes of Schizophrenia

938
Schizophrenia, a complex psychiatric disorder, has been historically misunderstood. Early psychological theories attributed its origins to childhood trauma and unresponsive parenting. However, contemporary research largely rejects these notions, favoring the vulnerability-stress hypothesis. This model proposes that individuals with a genetic predisposition to schizophrenia may develop the disorder following exposure to significant environmental stressors. Notably, studies on high-risk...
938
Psychosis: Goals of Pharmacotherapy01:26

Psychosis: Goals of Pharmacotherapy

680
Antipsychotic drugs are a crucial treatment method for acute and chronic psychoses, bipolar illness, and behavioral disorders. The selection of these drugs depends on several factors, including the state of the disease, clinical judgment, possible drug interactions, and the patient's sensitivity to adverse effects. In immediate scenarios, such as delirium and dementia, short-term treatment with low doses of high-potency typical or atypical agents can effectively manage symptom exacerbation.
680
Coping Strategies: Problem Focused01:27

Coping Strategies: Problem Focused

737
Coping strategies are methods people use to manage, tolerate, or reduce the effects of stressors. These strategies involve both behavioral and psychological actions to handle stressful situations. One common approach is problem-focused coping, which aims to change or eliminate the source of stress rather than merely addressing its consequences. This method involves taking direct action to resolve the issue causing stress.
For example, consider a student who struggles to understand their...
737
Personality Disorders: Paranoid and Schizoid01:22

Personality Disorders: Paranoid and Schizoid

1.1K
Personality disorders represent enduring cognition, affect, and behavior patterns that significantly deviate from societal norms. These maladaptive traits often lead to difficulties in various domains, including interpersonal relationships, occupational settings, and overall psychological well-being. Paranoid personality disorder and schizoid personality disorder are two distinct conditions marked by odd or eccentric behavior.
Paranoid Personality Disorder
Paranoid personality disorder is...
1.1K
Psychosis and Antipsychotic Drugs: Overview01:28

Psychosis and Antipsychotic Drugs: Overview

1.2K
The term "psychosis" refers to a spectrum of mental disorders characterized by abnormal thoughts, perceptions, and behaviors. It can manifest as mood disorders, dementia, delirium with psychotic features, substance-induced psychosis with psychotic features, brief psychotic disorder, delusional disorder, schizoaffective disorder, and schizophrenia. Among all these disorders, schizophrenia is the most common psychotic disorder, affecting 1% of the worldwide population. Psychotic...
1.2K
Coping Strategies: Emotion Focused01:20

Coping Strategies: Emotion Focused

800
Emotion-focused coping refers to a set of strategies aimed at managing the emotional impact of stressors, rather than directly addressing their causes. This approach involves altering one's emotional response to stressful situations to reduce their psychological effects. For example, individuals might talk with a friend or engage in activities like journaling to express their feelings. Such actions can help achieve emotional clarity or release, providing the psychological stability needed...
800

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Changes in leukocytes and CRP in different treatments of major depression.

Journal of neural transmission (Vienna, Austria : 1996)·2026
Same author

Brief Audiovisual Feedback Training Yields Long-Lasting Gains in Multisensory Integration and Speech Comprehension: Contributions of Different Cognitive Abilities.

Multisensory research·2026
Same author

Treatment options in sexually transgressive behaviors in adolescence: Review and presentation of a novel prevention program 180Grad.

Acta psychologica·2026
Same author

Factors Influencing the Prognostic Assessment of Patients with End-Stage Alcohol-Associated Liver Disease before Liver Transplantation.

European addiction research·2026
Same author

Resilience Mitigates the Link between Adverse Childhood Experiences and Musician's Dystonia: A Neuroendocrine and Psychological Perspective.

Tremor and other hyperkinetic movements (New York, N.Y.)·2026
Same author

Differential DNA-methylation of synaptic genes in CSF and blood in schizophrenia.

Schizophrenia (Heidelberg, Germany)·2026

Related Experiment Video

Updated: Apr 14, 2026

Investigating the Effects of Antipsychotics and Schizotypy on the N400 Using Event-Related Potentials and Semantic Categorization
12:00

Investigating the Effects of Antipsychotics and Schizotypy on the N400 Using Event-Related Potentials and Semantic Categorization

Published on: November 19, 2014

13.4K

Is conflict adaptation disrupted in schizophrenia? An ERP study.

Erfan Ghaneirad1, Anna Borgolte1, Gregor R Szycik1

  • 1Department of Psychiatry, Social Psychiatry and Psychotherapy, Hannover Medical School, Hannover, Germany.

Cognitive Neuropsychiatry
|April 13, 2026
PubMed
Summary

Individuals with schizophrenia (SZ) show preserved conflict adaptation, similar to healthy controls (HC). This suggests the congruency sequence effect (CSE), a marker of cognitive control, remains intact in SZ.

Keywords:
Congruency sequence effectERPcognitive controlconflict adaptationflanker task

More Related Videos

Exploring the Neural Correlates of Cognitive Reappraisal in Obsessive-Compulsive Disorder Using Task-based Functional Magnetic Resonance Imaging
09:14

Exploring the Neural Correlates of Cognitive Reappraisal in Obsessive-Compulsive Disorder Using Task-based Functional Magnetic Resonance Imaging

Published on: March 14, 2025

1.3K
Measurement of Fronto-limbic Activity Using an Emotional Oddball Task in Children with Familial High Risk for Schizophrenia
13:08

Measurement of Fronto-limbic Activity Using an Emotional Oddball Task in Children with Familial High Risk for Schizophrenia

Published on: December 2, 2015

9.6K

Related Experiment Videos

Last Updated: Apr 14, 2026

Investigating the Effects of Antipsychotics and Schizotypy on the N400 Using Event-Related Potentials and Semantic Categorization
12:00

Investigating the Effects of Antipsychotics and Schizotypy on the N400 Using Event-Related Potentials and Semantic Categorization

Published on: November 19, 2014

13.4K
Exploring the Neural Correlates of Cognitive Reappraisal in Obsessive-Compulsive Disorder Using Task-based Functional Magnetic Resonance Imaging
09:14

Exploring the Neural Correlates of Cognitive Reappraisal in Obsessive-Compulsive Disorder Using Task-based Functional Magnetic Resonance Imaging

Published on: March 14, 2025

1.3K
Measurement of Fronto-limbic Activity Using an Emotional Oddball Task in Children with Familial High Risk for Schizophrenia
13:08

Measurement of Fronto-limbic Activity Using an Emotional Oddball Task in Children with Familial High Risk for Schizophrenia

Published on: December 2, 2015

9.6K

Area of Science:

  • Cognitive Neuroscience
  • Psychiatry
  • Neuroscience

Background:

  • Schizophrenia (SZ) is characterized by cognitive control deficits.
  • The congruency sequence effect (CSE) is a key indicator of conflict adaptation.
  • Investigating the CSE in SZ can elucidate cognitive functioning in this population.

Purpose of the Study:

  • To investigate the congruency sequence effect (CSE) in individuals with schizophrenia (SZ).
  • To determine if the CSE is preserved in SZ despite known cognitive control deficits.
  • To compare the CSE between SZ and healthy controls (HC) using a rigorous methodology.

Main Methods:

  • A confound-minimized Flanker task was administered to 19 SZs and 19 HCs.
  • Congruent and incongruent trials were presented, with specific trial types excluded from analysis.
  • Behavioral (reaction time, accuracy) and electrophysiological (P2, N2, P3 event-related potentials) data were analyzed.

Main Results:

  • Both SZ and HC groups demonstrated a significant CSE, with faster and more accurate responses following congruent trials.
  • While SZs were slower overall, the magnitude and pattern of the CSE did not differ between groups.
  • No significant group differences were observed in event-related potential amplitudes (N2, P2, P3) related to the CSE.

Conclusions:

  • Individuals with schizophrenia exhibit behavioral and neural patterns of conflict adaptation comparable to healthy controls.
  • These findings suggest that the congruency sequence effect (CSE) may be preserved in medicated individuals with schizophrenia.
  • The study indicates that despite underlying brain abnormalities, core mechanisms of conflict adaptation remain functional in SZ.