Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Spongy Bone01:09

Spongy Bone

13.7K
All bones comprise an outer layer of compact bone, and an interior made up of spongy bone tissue, also called cancellous or trabecular bone. In long bones, spongy bone tissue is mainly found in the interior of the epiphyses (broad ends of the bone).
Spongy bone is more porous, and less dense compared to compact bone. It is composed of concentric lamellae that are arranged irregularly to form the trabecular network. In some bones, the spaces between trabeculae contain red marrow, where...
13.7K
Bone Disorders01:29

Bone Disorders

8.7K
Aging and its effect on bone remodeling is the most common cause of bone disorders. In young and healthy people, bone deposition and resorption happen at an equal rate to maintain optimal bone health.
Bone deposition is also affected by the levels of sex hormones like estrogen and testosterone that promote osteoblast activity and bone matrix synthesis. When the level of these hormones decreases due to aging, it causes a reduction in bone deposition. As a result, bone resorption by osteoclasts...
8.7K
Compact Bone01:27

Compact Bone

22.7K
Most bones contain compact and spongy osseous tissue, but their distribution and concentration vary based on the bone's overall function.
Compact bone, also called cortical bone, is the denser, stronger of the two types of bone tissue. It is found under the periosteum and in the diaphyses of long bones, where it provides support and protection. The microscopic structural unit of compact bone is called an osteon, or haversian system. Each osteon is composed of concentric rings of calcified...
22.7K
Bone Structure01:55

Bone Structure

53.2K
Within the skeletal system, the structure of a bone, or osseous tissue, can be exemplified in a long bone, like the femur, where there are two types of osseous tissue: cortical and cancellous.
53.2K
Fractures: Bone Repair01:27

Fractures: Bone Repair

6.8K
Treatment for a fracture is based on the type of break, the bone affected, and the patient's age.
Minor fractures with no bone displacement are treated by immobilizing the fractured bone using a cast or splint. However, in the case of fractures with displaced bones, the broken bones are repositioned before immobilization to ensure successful healing without deformation and loss of function. The realignment of fractured bone ends is performed through a process called reduction. If the...
6.8K
Osteoclasts in Bone Remodeling01:31

Osteoclasts in Bone Remodeling

4.9K
Osteoclasts are cells responsible for bone resorption and remodeling. They originate from hematopoietic progenitor cells present in the bone marrow. Numerous progenitor cells fuse to form multinucleated cells, each with 10-20 nuclei. A single osteoclast has a diameter of 150 to 200 µM. These cells have ruffled borders that break down the underlying bone tissue and release minerals such as calcium into the blood in bone resorption. Osteoclasts cling to bones with their ruffled edges during...
4.9K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Preserving Trabecular Bone Structure in Gross Specimens with Paraffin Wax for the Study of Osteoporosis.

Journal of plastination·2026
Same author

Push-Up Techniques Affect Elbows and Shoulders: How Should They Be Used?

Handchirurgie, Mikrochirurgie, plastische Chirurgie : Organ der Deutschsprachigen Arbeitsgemeinschaft fur Handchirurgie : Organ der Deutschsprachigen Arbeitsgemeinschaft fur Mikrochirurgie der Peripheren Nerven und Gefasse : Organ der V...·2026
Same author

Excision of the Proximal Pole of the Scaphoid Affects the Midcarpal Joint.

Journal of wrist surgery·2026
Same author

Preoperative CT-Based Finite Element Vertebral Modulus Analysis Predicts Bone Quality-Related Complications After Lumbar Spine Fusion.

Spine·2026
Same author

Challenges in Measuring Outcomes in the Wrist.

Journal of wrist surgery·2026
Same author

Duplex Ultrasound Differentiation of Popliteal Artery Spasm Versus True Arterial Injury During Knee Surgery: A Case Report.

Journal of orthopaedic case reports·2026

Related Experiment Video

Updated: Apr 14, 2026

Author Spotlight: An Economic and Efficient Method for Quantitative Evaluation of Bone Microarchitecture in a Murine Osteoporosis Model
06:59

Author Spotlight: An Economic and Efficient Method for Quantitative Evaluation of Bone Microarchitecture in a Murine Osteoporosis Model

Published on: September 8, 2023

4.0K

Wrist MRI trabecular structure and osteoporosis-a pilot study.

Allison Ariniello1, Xiaoliu Zhang2, Punam K Saha2

  • 1Department of Orthopedic Surgery, NYU Grossman School of Medicine, NY 10016, United States.

The British Journal of Radiology
|April 13, 2026
PubMed
Summary
This summary is machine-generated.

Wrist MRI shows significant differences in trabecular bone structure between individuals at high and low risk for fragility fractures. This technique shows promise for early osteoporosis screening and prevention.

Keywords:
MRIdiagnosisdistal radiusosteoporosistrabecular structurewrist

More Related Videos

Semiautomated Longitudinal Microcomputed Tomography-based Quantitative Structural Analysis of a Nude Rat Osteoporosis-related Vertebral Fracture Model
07:12

Semiautomated Longitudinal Microcomputed Tomography-based Quantitative Structural Analysis of a Nude Rat Osteoporosis-related Vertebral Fracture Model

Published on: September 28, 2017

8.7K
Outer-Boundary Assisted Segmentation and Quantification of Trabecular Bones by an Imagej Plugin
09:36

Outer-Boundary Assisted Segmentation and Quantification of Trabecular Bones by an Imagej Plugin

Published on: March 14, 2018

9.9K

Related Experiment Videos

Last Updated: Apr 14, 2026

Author Spotlight: An Economic and Efficient Method for Quantitative Evaluation of Bone Microarchitecture in a Murine Osteoporosis Model
06:59

Author Spotlight: An Economic and Efficient Method for Quantitative Evaluation of Bone Microarchitecture in a Murine Osteoporosis Model

Published on: September 8, 2023

4.0K
Semiautomated Longitudinal Microcomputed Tomography-based Quantitative Structural Analysis of a Nude Rat Osteoporosis-related Vertebral Fracture Model
07:12

Semiautomated Longitudinal Microcomputed Tomography-based Quantitative Structural Analysis of a Nude Rat Osteoporosis-related Vertebral Fracture Model

Published on: September 28, 2017

8.7K
Outer-Boundary Assisted Segmentation and Quantification of Trabecular Bones by an Imagej Plugin
09:36

Outer-Boundary Assisted Segmentation and Quantification of Trabecular Bones by an Imagej Plugin

Published on: March 14, 2018

9.9K

Area of Science:

  • Orthopedics and Imaging Science
  • Bone Biology and Osteoporosis Research

Background:

  • Osteoporosis and fragility fractures pose a growing health concern.
  • Dual-energy X-ray absorptiometry (DEXA) is limited in predicting fragility fractures.
  • Trabecular structure, particularly in the distal radius, may offer earlier indicators of osteoporosis.

Purpose of the Study:

  • To compare distal radius trabecular structure using MRI in patients with normal versus increased risk for fragility fractures.
  • To evaluate the potential of wrist MRI as a sensitive and specific screening tool for early osteoporosis.

Main Methods:

  • Ultra-short-echo-time (UTE) MRI of the distal radius was performed on 10 low-risk and 9 high-risk subjects.
  • Analysis included trabecular parameters such as plate-width, plate-rod ratio, volume fractions, thickness, pore size, and density.
  • Statistical analysis (T-test/Mann-Whitney U) and calculation of sensitivity/specificity were used to compare groups.

Main Results:

  • Statistically significant differences in trabecular structure were observed between low- and high-risk groups for most parameters (p < 0.05).
  • Trabecular thickness was the only parameter not showing a significant difference between groups.
  • The study demonstrated optimal sensitivity and specificity for wrist MRI in predicting osteoporosis.

Conclusions:

  • Wrist MRI is a feasible tool for screening early osteoporosis.
  • This imaging modality may enable timely prevention strategies for fragility fractures.
  • Further longitudinal studies are required to confirm its ability to predict fragility fractures.