Related Experiment Video
Updated: Apr 14, 2026
08:49
Use of Two Intracorporeal Ventricular Assist Devices As a Total Artificial Heart
Published on: May 11, 2018
10.1K
Joint Arthroplasty in Patients With Left Ventricular Assist Devices
Audrey N Kobayashi1, Stephen C Moye1, Clay B Beagles1
1Department of Orthopaedic Surgery, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.
Arthroplasty Today
|April 13, 2026
Summary
Joint arthroplasty (JA) in patients with left ventricular assist devices (LVADs) shows similar postoperative complication rates compared to controls. This largest study to date indicates LVAD patients can safely undergo JA with comparable outcomes.
Area of Science:
- Cardiology
- Orthopedic Surgery
- Medical Devices
Background:
- Limited case series exist on joint arthroplasty (JA) in patients with left ventricular assist devices (LVADs).
- This study represents the largest retrospective matched cohort comparing JA outcomes in LVAD patients versus controls.
Purpose of the Study:
- To compare postoperative complications of JA in patients with and without LVADs.
- To evaluate the safety and efficacy of JA in the LVAD population.
Main Methods:
- Retrospective matched cohort study (2014-2023) comparing 13 JA patients with LVADs to 39 controls.
- Matched for demographics, comorbidities, and arthroplasty type.
- Assessed complications including ED visits, infections, thrombosis, transfusions, functional outcomes, reoperations, survival, and mortality.
Main Results:
- LVAD patients showed similar rates of 90-day ED visits, 1-year infections, thrombosis, and transfusions compared to controls.
- Patient-reported physical function scores and 2-year survival/mortality were comparable between groups.
- Reoperation rates were also similar between the LVAD and control groups.
Conclusions:
- This study is the largest series of patients undergoing JA after LVAD implantation.
- JA in patients with LVADs demonstrates similar 1-year postoperative complication rates to matched non-LVAD counterparts.
Related Concept Videos
01:25Aortic Regurgitation III: Medical Management
562
Aortic regurgitation (AR) is when the aortic valve does not close or seal properly, leading to backward blood circulation from the aorta into the left ventricle during diastole. Common causes of AR include rheumatic heart disease, congenital valve defects, and aortic root dilation. Managing AR requires a multifaceted approach to alleviate symptoms, preserve left ventricular function, and address the underlying cause of the regurgitation. Patients with symptomatic AR or significant left...
562
01:29Cardiomyopathy V: Interprofessional Care
702
Managing cardiomyopathy involves addressing underlying or precipitating causes, treating heart failure with medications, and implementing dietary changes and a balanced exercise and rest regimen.Lifestyle ModificationsCardiomyopathy patients should adopt a low-sodium diet to reduce fluid retention and manage heart failure. A personalized exercise and rest plan helps maintain physical fitness without overstraining the heart. Avoiding alcohol and tobacco is essential to prevent further damage to...
702
01:22Heart Failure VI: Adjunct Therapies
602
Additional therapies for treating patients with heart failure (HF) may include procedural interventions, supplemental oxygen, the management of sleep disorders, and nutritional therapy.Procedural InterventionsImplantable Cardioverter-Defibrillator: For patients at risk of life-threatening arrhythmias due to severe left ventricular dysfunction, an Implantable Cardioverter-Defibrillator (ICD) can detect and terminate these arrhythmias, preventing sudden cardiac death and improving survival rates.
602
01:26Mitral Stenosis III: Medical Management
483
Mitral stenosis, a condition marked by the narrowing of the mitral valve, necessitates an integrated approach for effective management. This approach includes preventative measures, medical therapy, and surgical interventions to reduce symptoms and prevent complications.PreventionPrevention of mitral stenosis primarily focuses on reducing the incidence of bacterial infections, particularly streptococcal infections, which can lead to rheumatic fever and subsequent valvular damage. Timely...
483
01:21Rheumatic Heart Disease III: Medical Management
523
Rheumatic heart disease (RHD) management can be divided into two main strategies: prevention and long-term management.Primary PreventionPrimary prevention focuses on timely diagnosis and management of group A streptococcal pharyngitis to prevent acute rheumatic fever. The most widely used antibiotic for treating this condition is intramuscular benzathine penicillin G.Acute Rheumatic Fever TreatmentThe primary treatment goal for a patient diagnosed with acute rheumatic fever is to suppress the...
523
01:20Rheumatic Heart Disease IV: Nursing Management
465
AssessmentA comprehensive assessment is essential in managing a patient with rheumatic heart disease (RHD). Begin with obtaining a detailed medical history, including recent streptococcal infections, a history of rheumatic fever, or previously diagnosed rheumatic heart disease. Assess the patient for symptoms such as fever, chest pain, widespread joint pain (arthralgia), tachycardia, pericardial friction rub, muffled heart sounds, heart murmurs, peripheral edema, subcutaneous nodules, and...
465