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Chronic Khat Use as a Possible Contributor to Advanced Liver Cirrhosis: A Case Report

Ahmed A Kassem1

  • 1General Practice, Sheikh Khalifa Bin Zayed Al Nahyan Hospital, Hadibu, YEM.

Cureus
|April 13, 2026
PubMed

Insights

Chronic khat (Catha edulis) use may contribute to advanced liver disease, including cirrhosis and pulmonary hypertension. This case highlights the importance of considering khat exposure in patients with unexplained liver conditions.

Area of Science:

  • Hepatology
  • Pulmonology
  • Toxicology

Background:

  • Khat (Catha edulis) is a stimulant plant widely used in Yemen and surrounding regions.
  • Chronic substance use can lead to various organ toxicities, including liver damage.
  • The long-term effects of khat use on liver health are not well-established.

Keywords:
immune mediated hepatitiskhat and liver diseasekhat chewingliver damageliver functionliver transplantportal hypertensiontransjugular intrahepatic portosystemic shunt (tips)

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