Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Parkinson's Disease: Overview01:15

Parkinson's Disease: Overview

2.4K
Neurodegenerative disorders are progressive diseases that cause irreversible damage and loss to neurons in specific brain areas. Examples of these disorders include Parkinson's disease, Alzheimer's disease, Multiple Sclerosis (MS), and Amyotrophic Lateral Sclerosis (ALS). These disorders share characteristics such as proteinopathies, selective neuronal vulnerability, and a complex interplay between genetic and environmental factors. The primary therapeutic goal for these conditions is...
2.4K
Parkinson's Disease: Treatment01:24

Parkinson's Disease: Treatment

1.4K
Neurodegenerative disorders, such as Parkinson's Disease (PD), involve the gradual and irreversible destruction of neurons in particular brain areas. These disorders exhibit standard features like proteinopathies, selective vulnerability of some neurons, and an interaction of intrinsic properties, genetics, and environmental influences in neural injury.
Parkinson's Disease is primarily a result of the loss of dopaminergic neurons in the substantia nigra pars compacta. The cornerstone of...
1.4K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Sensor-derived heel pressure metrics capture reversible gait dysfunction beyond conventional gait measures in normal pressure hydrocephalus.

Journal of neuroengineering and rehabilitation·2026
Same author

Role of Fat-Free Mass-Adjusted Cardiorespiratory Fitness in Predicting Hospitalization Risk in Patients with Heart Failure.

Yonsei medical journal·2026
Same author

Promoting Rehabilitation Using a Multimodal Internet of Things-Based Patient Monitoring System in a Smart Hospital.

IEEE journal of translational engineering in health and medicine·2026
Same author

Tracing the global spread of maize (Zea mays L.) through plastome analysis of landraces.

BMC plant biology·2025
Same author

Serial Assessment of Gait Changes After Interventions Using Smart Insole in a Patient With iNPH: A Proof-of-Concept Case Report.

Brain & NeuroRehabilitation·2025
Same author

Quality Analysis of YouTube-Based Exercise Programs for Typically Developing Children: Content Analysis.

Healthcare (Basel, Switzerland)·2025

Related Experiment Video

Updated: Apr 14, 2026

Dynamic Digital Biomarkers of Motor and Cognitive Function in Parkinson's Disease
10:28

Dynamic Digital Biomarkers of Motor and Cognitive Function in Parkinson's Disease

Published on: July 24, 2019

16.6K

Insole-Derived Plantar Pressure Variability Reveals Dual-Task Gait Differences in Early-Stage Parkinson's Disease.

Ye Joon Kim1, Seung-Ick Choi2, Huiwoo Yang3

  • 1Department of Rehabilitation Medicine, Yongin Severance HospitalYonsei University College of Medicine Yongin-si 16995 Republic of Korea.

IEEE Journal of Translational Engineering in Health and Medicine
|April 13, 2026
PubMed
Summary

Plantar pressure analysis using sensor insoles reveals subtle gait changes in Parkinson's disease (PD) patients during dual-task walking. These metrics offer greater sensitivity than traditional measures for detecting dual-task costs in PD.

Keywords:
Gait analysisParkinson’sgait disordersneurologicwearable electronic devices

More Related Videos

Clinical Assessment of Spatiotemporal Gait Parameters in Patients and Older Adults
08:56

Clinical Assessment of Spatiotemporal Gait Parameters in Patients and Older Adults

Published on: November 7, 2014

14.5K
Motor Dual-Tasks for Gait Analysis and Evaluation in Post-Stroke Patients
05:23

Motor Dual-Tasks for Gait Analysis and Evaluation in Post-Stroke Patients

Published on: March 11, 2021

3.1K

Related Experiment Videos

Last Updated: Apr 14, 2026

Dynamic Digital Biomarkers of Motor and Cognitive Function in Parkinson's Disease
10:28

Dynamic Digital Biomarkers of Motor and Cognitive Function in Parkinson's Disease

Published on: July 24, 2019

16.6K
Clinical Assessment of Spatiotemporal Gait Parameters in Patients and Older Adults
08:56

Clinical Assessment of Spatiotemporal Gait Parameters in Patients and Older Adults

Published on: November 7, 2014

14.5K
Motor Dual-Tasks for Gait Analysis and Evaluation in Post-Stroke Patients
05:23

Motor Dual-Tasks for Gait Analysis and Evaluation in Post-Stroke Patients

Published on: March 11, 2021

3.1K

Area of Science:

  • Biomechanics
  • Neuroscience
  • Clinical Gait Analysis

Background:

  • Gait disturbances in Parkinson's disease (PD) reflect impaired motor automaticity, especially during cognitive tasks.
  • Conventional spatiotemporal gait parameters have limited sensitivity in detecting dual-task costs in PD patients.

Purpose of the Study:

  • To characterize plantar pressure alterations during dual-task walking in early-stage PD (EPD) using sensor-based insoles.
  • To compare the sensitivity of plantar pressure metrics with conventional gait metrics for assessing dual-task costs in EPD.

Main Methods:

  • On-site validation of insole-derived parameters against 3D motion analysis in healthy adults.
  • Cross-sectional study comparing spatiotemporal and plantar pressure metrics in healthy young adults, healthy older adults, and EPD patients.
  • 10-meter walking tests under single- and dual-task (serial subtraction) conditions.

Main Results:

  • Insole parameters demonstrated good validity compared to 3D motion analysis.
  • EPD patients showed slower velocity, shorter stride length, and greater gait variability under single-task conditions.
  • Plantar pressure analysis revealed reduced peak pressures and increased heel variability in EPD patients, with distinct dual-task alterations in heel loading and variability.

Conclusions:

  • Plantar pressure metrics offer enhanced sensitivity over spatiotemporal parameters for detecting dual-task gait alterations in PD.
  • Sensor-based insoles provide practical and sensitive gait metrics for clinical assessment of subtle gait changes in PD.