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Patient Safety in Anticoagulation: Implementing Safety-II and FRAM in the Medical Curriculum
Lauren S Baidjoe1, Liselotte M van Dijk2, Mirjam Simoons1,3
1Department of Hospital Pharmacy, Erasmus MC, University Medical Center Rotterdam, The Netherlands.
Perspectives on Medical Education
|April 13, 2026
Summary
This study introduces Safety-II concepts into medical education to enhance patient safety. By focusing on adaptability and resilience, it improves anticoagulation management and fosters a culture of continuous learning in healthcare professionals.
Area of Science:
- Medical Education
- Patient Safety
- Healthcare Systems
Background:
- Traditional error-focused approaches to medication safety limit learning opportunities.
- Safety-II emphasizes healthcare professionals' adaptability and resilience in complex environments, complementing Safety-I's focus on problem identification.
Purpose of the Study:
- To describe an innovative educational intervention integrating Safety-II, Functional Resonance Analysis Method (FRAM), and anticoagulation management.
- To enhance master's-level medical students' understanding of anticoagulation processes and system strengths in perioperative care.
Main Methods:
- Integration of Safety-II principles and FRAM into an existing medication safety course.
- Utilized clinical case studies, FRAM model creation, and reflective clerkship experiences.
- Incorporated active learning strategies like 'flipped classroom' and 'just-in-time teaching'.
Main Results:
- Successful integration into the medical curriculum, with iterative refinement based on feedback and learning analytics.
- Enhanced students' ability to recognize system strengths and adapt to complex situations.
- Expanded implementation to cross-disciplinary education for specialist healthcare professionals.
Conclusions:
- The Safety-II educational intervention effectively enhances medication safety education.
- Fosters a culture of safer, more resilient care by prioritizing adaptability and continuous learning across healthcare disciplines.

