Related Experiment Video
Updated: Apr 14, 2026
Tubal Cytology of the Fallopian Tube as a Promising Tool for Ovarian Cancer Early Detection
Published on: July 25, 2017
Fertility-Sparing Management of HPV-Associated FIGO IB1 Mucinous Cervical Adenocarcinoma With Signet-Ring Cell
Luiz Felipe Lessa Ortiz1, Amanda Lino de Faria Lessa1, Rafael Dyer Rodrigues de Moraes2
1GAVVA Clínica-Medicina Reprodutiva e Oncofertilidade, São Paulo, Brazil.
Background:
Fertility-sparing surgery is an increasingly accepted option in carefully selected patients with early-stage cervical cancer. Radical vaginal trachelectomy combined with sentinel lymph node (SLN) mapping offers oncologic safety while preserving reproductive potential.
Case:
A 29-year-old nulliparous woman with FIGO stage IB1 poorly differentiated HPV-associated mucinous cervical adenocarcinoma with signet-ring cell features underwent radical vaginal trachelectomy and bilateral laparoscopic SLN mapping using indocyanine green (ICG). No nodal metastases were identified. Surgical margins were negative, and an abdominal cervical cerclage was placed. At 24 months of follow-up, the patient remains disease-free and is receiving counseling regarding assisted reproductive technologies.
Conclusion:
Fertility-preserving surgery may be safely performed in selected early-stage cervical cancer patients when combined with appropriate surgical staging and close follow-up. This case adds to the limited literature regarding the conservative management of high-grade mucinous adenocarcinomas with signet-ring cell morphology.
More Related Videos
05:46Introduction of Intracapsular Rotary-cut Procedures IRCP: A Modified Hysteromyomectomy Procedures Facilitating Fertility Preservation
Published on: January 17, 2019
06:57Chromogenic In Situ Hybridization as a Tool for HPV-Related Head and Neck Cancer Diagnosis
Published on: June 14, 2019