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Fabrication and Design of Wood-Based High-Performance Composites

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Recent Advances on Starch-Based Biomaterials: A Review.

Renan N Araújo¹, Bruna S Bitencourt^1,2, Samile B de Aguiar¹

¹Department of Physical Chemistry, São Carlos Institute of Chemistry (IQSC), University of São Paulo (USP), São Carlos 13566-590, Brazil.

ACS Polymers Au

|April 13, 2026

Summary

This summary is machine-generated.

Starch biomaterials show promise for biomedical applications like wound dressings and drug delivery due to their biocompatibility. However, most research needs more in vivo data and scalability assessments for real-world use.

Keywords:

biomaterials drug delivery systems hybrid and smart biomaterials modified starch scaffolds starch structure and physical properties wound dressings

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Area of Science:

Biomaterials Science
Polymer Chemistry
Biomedical Engineering

Background:

Starch is a versatile, biocompatible, and biodegradable polymer with potential for biomedical applications.
Starch-based biomaterials are being developed for sustainable and eco-friendly medical uses.
Current research focuses on modifying starch to enhance its properties for various biomedical applications.

Purpose of the Study:

To review recent advancements in starch-based biomaterials for biomedical applications.
To synthesize current literature on starch biomaterials in wound dressings, drug delivery, regenerative medicine, and tissue engineering.
To identify gaps in research regarding in vivo data and large-scale production feasibility.

Main Methods:

Comprehensive literature review of recent studies on starch biomaterials.
Analysis of advancements in material properties, including biodegradability, biocompatibility, and mechanical strength.
Evaluation of applications in wound healing, drug delivery, and tissue engineering.

Main Results:

Starch biomaterials demonstrate adequate biodegradability, active functions, good biocompatibility, and mechanical properties.
Significant progress has been made in developing starch-based scaffolds for regenerative medicine and tissue engineering.
Key applications include advanced wound dressings and sophisticated drug delivery systems.

Conclusions:

Starch-based biomaterials offer significant potential for diverse biomedical applications.
Further research is crucial to bridge the gap between in vitro findings and in vivo validation.
Scalability assessments, including economic and operational feasibility, are essential for clinical translation and manufacturing.