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Recurrent Toxin-Mediated Perineal Erythema: Eleven Pediatric Cases
Andrés Carvajal1, Romina Cabrera1, Margarita Larralde1,2
1Pediatric Dermatology Section, Hospital General de Agudos J. M. Ramos Mejía, Buenos Aires, Argentina.
Pediatric Dermatology
|April 13, 2026
Summary
Recurrent toxin-mediated perineal erythema (RTMPE) is a skin condition in children. Early diagnosis and oral antibiotic treatment showed good results in pediatric patients.
Area of Science:
- Dermatology
- Pediatric Dermatology
- Microbiology
Background:
- Recurrent toxin-mediated perineal erythema (RTMPE) is a T-lymphocyte response to bacterial toxins.
- While often seen in adolescents, pediatric RTMPE cases are rising.
- Staphylococcus aureus and Streptococcus pyogenes are implicated bacterial culprits.
Purpose of the Study:
- To describe RTMPE in pediatric patients.
- To evaluate the response to oral antibiotic therapy in children with RTMPE.
Main Methods:
- Retrospective case series.
- Eleven pediatric patients diagnosed with RTMPE were identified.
- Treatment and outcomes were reviewed.
Main Results:
- Eleven pediatric patients with RTMPE were identified.
- All patients showed a good response to oral antibiotic treatment.
- No significant adverse events were reported.
Conclusions:
- RTMPE is increasingly recognized in pediatric populations.
- Oral antibiotics are an effective treatment for pediatric RTMPE.
- Prompt diagnosis and treatment are crucial for favorable outcomes.
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