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Updated: Jun 22, 2026

Development of Amelogenin-chitosan Hydrogel for In Vitro Enamel Regrowth with a Dense Interface
Published on: July 10, 2014
Application of Polymers in Advanced Materials for Enamel and Dentine Remineralization
Zichen Wu1, Le Zhang1, Jingwen Wu2
1Paediatric Dentistry and Orthodontics, Faculty of Dentistry, The University of Hong Kong, 34 Hospital Road, Hong Kong SAR 999077, PR China.
Abstract:
Dental caries, the most common oral disease with a worldwide burden, causes structural damage to enamel and dentine. Considering the limitations of conventional restorative approaches and the dynamic nature of caries, biomimetic remineralization strategies offer a promising alternative for restoring tooth structure. Central to many of these strategies is the use of polymers to emulate the role of macromolecular templates in natural mineralization processes. This review summarizes the polymers applied for biomimetic mineralization of enamel and dentine according to their primary functions. Furthermore, perspectives on the trends and challenges for future research on polymeric biomaterials for enamel and dentine repair are also presented.
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