Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Pathophysiology of Diabetes01:20

Pathophysiology of Diabetes

4.6K
Diabetes mellitus is a chronic metabolic disorder characterized by hyperglycemia. The four categories of diabetes are type 1 diabetes, type 2 diabetes, other specific types of diabetes, and gestational diabetes.
Type 1 diabetes is characterized by autoimmune-mediated destruction of pancreatic β cells, with environmental factors potentially triggering this process in genetically susceptible individuals. Despite many not having a family history, certain genes increase susceptibility,...
4.6K
Diabetes: Symptoms, Diagnosis, and Complications01:15

Diabetes: Symptoms, Diagnosis, and Complications

2.9K
For most patients, experiencing several weeks of polyuria, polydipsia, fatigue, and significant weight loss may indicate the presence of diabetes. Furthermore, adults displaying the phenotypic appearance of type 2 diabetes (particularly those who are obese and not initially insulin-requiring), may have islet cell autoantibodies, suggesting autoimmune-mediated β cell destruction and a diagnosis of latent autoimmune diabetes of adults (LADA). The categorization of glucose homeostasis is...
2.9K
Diabetes Mellitus: Type 2 and Gestational01:22

Diabetes Mellitus: Type 2 and Gestational

5.8K
Type 2 diabetes, characterized by insulin resistance, arises when the insulin receptors on cells lose responsiveness to insulin, diminishing the cell's capacity to take up glucose, resulting in elevated blood glucose levels. To receive a diagnosis of Type 2 diabetes, a series of blood glucose tests are necessary to assess whether the blood glucose falls within normal parameters. If the result is out of the normal range, a patient may be diagnosed as prediabetic or diabetic, depending on the...
5.8K
Gastritis-II: Pathophysiology01:17

Gastritis-II: Pathophysiology

1.8K
Gastritis is marked by disruption of the mucosal barrier that usually protects the stomach tissue from digestive juices and manifests in acute and chronic forms.
In acute gastritis, the gastric mucosa becomes swollen and red and undergoes superficial erosion. Superficial ulceration may lead to bleeding.
In chronic gastritis, persistent or repeated insults lead to chronic inflammatory changes and, eventually, thinning or atrophy of the gastric tissue.
Gastritis can stem from various causes, each...
1.8K
Chronic Pancreatitis I: Introduction01:24

Chronic Pancreatitis I: Introduction

926
The pancreas, an elongated and flat gland situated behind the stomach, serves a vital function in digesting food and managing blood sugar levels.
Pancreatitis is the inflammation of the pancreas, which occurs when the immune system becomes active and causes swelling, pain, and disruptions in organ function. Pancreatitis can manifest as either an acute or chronic condition.
Acute pancreatitis arises suddenly and lasts for a brief duration, while chronic pancreatitis is a long-term affliction...
926
Carbohydrate Metabolism01:36

Carbohydrate Metabolism

15.2K
Carbohydrates are polymers composed of molecules containing atoms of carbon, hydrogen and oxygen. One gram of carbohydrate can provide four kilo-calories of energy, which makes it the most efficient instant energy source.
Starch accounts for approximately 60% of the carbohydrates consumed by humans. Since amylase enzymes cannot function in the stomach's acidic environment, starch can only be digested in the mouth and small intestine. Simple sugars are found naturally in milk and fruits in...
15.2K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Expert Clinical Consensus on Body Surface Gastric Mapping Phenotypes for Gastroduodenal Disorders: 'Auckland Classification' v1.0.

Neurogastroenterology and motility·2026
Same author

The effects of 10 months of exercise on circulating ketone body concentration among children.

Pediatric research·2026
Same author

Advancing quantitative outcome measurement in therapeutic dance.

Frontiers in psychology·2026
Same author

Fall-Related Emergency Department Visits Among Adults With and Without Intellectual and Developmental Disabilities or Cerebral Palsy.

Annals of family medicine·2026
Same author

Letter: Gastroparesis in Lung Transplantation: Time to Reframe and Standardize Post-Transplant Foregut Motility Evaluation: Authors' Reply.

Alimentary pharmacology & therapeutics·2026
Same author

CT Esophagram Demonstrating Bezoar in a Colonic Interposition Conduit.

The American journal of gastroenterology·2026
Same journal

GLP-1 Receptor Agonists and Hepatic Encephalopathy in Cirrhosis: A Protective Signal Requiring Cancer and Nutritional Phenotyping.

Journal of clinical gastroenterology·2026
Same journal

Endoscopic Incisional Therapy for Benign Esophageal Strictures: A Systematic Review and Meta-Analysis.

Journal of clinical gastroenterology·2026
Same journal

International Consensus Statements on the Use of Topical Endoscopic Hemostatic Powders in the Treatment of Acute Gastrointestinal Bleeding.

Journal of clinical gastroenterology·2026
Same journal

Do Risk Factors for Reflux Symptoms After Peroral Endoscopic Myotomy Necessarily Increase the Occurrence of Postoperative Gastroesophageal Reflux?

Journal of clinical gastroenterology·2026
Same journal

Subgroup Stratification by Regimen, Geography, and Population Is Necessary to Validate Nitazoxanide-based Helicobacter pylori Eradication Therapy.

Journal of clinical gastroenterology·2026
Same journal

The Impact of Glucagon-Like Peptide 1 Receptor Agonists Versus Diabetes Mellitus on Endoscopic Procedures: A Case-Control Study From a Large Tertiary Care Health System.

Journal of clinical gastroenterology·2026
See all related articles

Related Experiment Video

Updated: Apr 15, 2026

Assessment of Gastric Emptying in Non-obese Diabetic Mice Using a [13C]-octanoic Acid Breath Test
12:24

Assessment of Gastric Emptying in Non-obese Diabetic Mice Using a [13C]-octanoic Acid Breath Test

Published on: March 23, 2013

14.2K

Diabetic Gastroparesis in Evolution.

Audrey Eubanks1, Deborah A Jehu1, Chuma Obineme2

  • 1School of Public Health, Augusta University, Augusta, GA.

Journal of Clinical Gastroenterology
|April 13, 2026
PubMed
Summary
This summary is machine-generated.

Diabetic gastroparesis (DGp) is a complex diabetes complication affecting gastric emptying. This review details its evolving diagnostics and treatments, from traditional methods to emerging gut-brain axis strategies.

Keywords:
G-POEMcapsulesdiabetic gastroparesisgastrointestinal motilityneuromodulation

More Related Videos

Author Spotlight: Integrating Tai Chi with Mindfulness Training to Achieve an Effective Mind-Body Exercise
05:06

Author Spotlight: Integrating Tai Chi with Mindfulness Training to Achieve an Effective Mind-Body Exercise

Published on: July 14, 2023

2.6K
Author Spotlight: Genetically Engineered Mouse Models and Pathological Characterization of Neurofibromatosis Type 1 Associated Tumors
08:57

Author Spotlight: Genetically Engineered Mouse Models and Pathological Characterization of Neurofibromatosis Type 1 Associated Tumors

Published on: May 17, 2024

2.8K

Related Experiment Videos

Last Updated: Apr 15, 2026

Assessment of Gastric Emptying in Non-obese Diabetic Mice Using a [13C]-octanoic Acid Breath Test
12:24

Assessment of Gastric Emptying in Non-obese Diabetic Mice Using a [13C]-octanoic Acid Breath Test

Published on: March 23, 2013

14.2K
Author Spotlight: Integrating Tai Chi with Mindfulness Training to Achieve an Effective Mind-Body Exercise
05:06

Author Spotlight: Integrating Tai Chi with Mindfulness Training to Achieve an Effective Mind-Body Exercise

Published on: July 14, 2023

2.6K
Author Spotlight: Genetically Engineered Mouse Models and Pathological Characterization of Neurofibromatosis Type 1 Associated Tumors
08:57

Author Spotlight: Genetically Engineered Mouse Models and Pathological Characterization of Neurofibromatosis Type 1 Associated Tumors

Published on: May 17, 2024

2.8K

Area of Science:

  • Gastroenterology
  • Endocrinology
  • Medical Diagnostics

Background:

  • Diabetic gastroparesis (DGp) is a chronic complication of diabetes mellitus, marked by delayed gastric emptying.
  • Symptoms like nausea, vomiting, and bloating are common but not always proportional to gastric emptying delay.

Purpose of the Study:

  • To provide a comprehensive, chronological review of the evolving landscape of diabetic gastroparesis.
  • To integrate historical perspectives with contemporary advances in DGp diagnostics and therapeutics.

Main Methods:

  • A targeted narrative synthesis of literature from PubMed, Embase, and Scopus (2013-2025).
  • Screening and thematic organization of relevant English-language articles into diagnostics, therapeutics, and emerging interventions.

Main Results:

  • Diagnostic modalities have advanced from gastric emptying scintigraphy to wireless motility capsule, gas-sensing capsule, body surface gastric mapping, and dynamic gastric MRI.
  • Therapeutic evolution includes moving beyond dopamine receptor antagonists to nonpharmacologic gut-brain axis strategies and pylorus-directed procedures.

Conclusions:

  • Understanding of DGp has significantly evolved over six decades.
  • Integrating historical and current knowledge provides context for future research to improve patient outcomes in diabetic gastroparesis.