Related Experiment Video
Updated: Apr 15, 2026

Author Spotlight: Enhancing Coronary Artery Revascularization
Published on: September 15, 2023
Left Main Stem Perforation: Management Strategies in a Potentially Catastrophic Event
Hilal Khan1, Mohamed Farag1,2, Scott Wilkes3
1Cardiothoracic Centre, Freeman Hospital, Newcastle-upon-Tyne, UK.
Insights
Left main stem perforation during PCI is a critical complication. This case highlights successful management using a covered stent and specialized techniques to restore coronary flow and ensure patient survival.
Area of Science:
- Cardiovascular Interventions
- Interventional Cardiology
- Coronary Artery Disease
Background:
- Left main stem (LMS) coronary perforation is a rare but life-threatening complication during percutaneous coronary intervention (PCI).
- Prompt recognition and emergent management are crucial for patient survival.
- LMS perforation presents unique challenges due to hemodynamic instability and the critical nature of the vessel.
Abstract:
Left main stem coronary perforation is a potentially fatal complication of percutaneous coronary intervention if not recognized early and treated emergently. Treating left main stem perforation can be challenging due to the significant hemodynamic effect of one of the important steps, namely balloon tamponade. Managing such perforation requires speed, precision, and a clear systematic approach to help save lives. We present a case of left main stem perforation that occurred during chronic total occlusion percutaneous coronary intervention which was treated with a covered stent across the left main stem into the left anterior descending artery. Restoration of flow into the circumflex was achieved by using a penetrating wire to cross into the circumflex, achieving hemostasis and preserving coronary flow into both epicardial coronary arteries. We describe further bailout strategies for dealing with left main stem perforations, including left main covered stenting with jailed side branch balloon and the simultaneous kissing stent technique.
More Related Videos
09:37Permanent Ligation of the Left Anterior Descending Coronary Artery in Mice: A Model of Post-myocardial Infarction Remodelling and Heart Failure
Published on: December 2, 2014
13:10Direct Re-implantation of Left Coronary Artery into the Aorta in Adults with Anomalous Origin of Left Coronary Artery from the Pulmonary Artery ALCAPA
Published on: April 24, 2017
Related Concept Videos
Esophageal Perforation-II: Clinical Manifestations and Management
Clinical Manifestations:
Pericarditis III: Medical Management
Acute Coronary Syndrome IV: Interprofessional Care
Aneurysm III: Interprofessional Care
Mitral Stenosis III: Medical Management
Cardiomyopathy V: Interprofessional Care