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Association Between Occupation and Cancer Risk: A Large-scale Case-control Study in Japan

Kota Fukai1, Shoko Nakazawa, Kosuke Sakai

  • 1From the Department of Preventive Medicine, Tokai University School of Medicine, Isehara, Japan (K.F., S.N., K. Sakai, Y.F., M.T.); Department of Ophthalmology, The Jikei University School of Medicine, Tokyo, Japan (K. Sano); Department of Public Health, Shizuoka Graduate University of Public Health, Shizuoka, Japan (N.K.); Center for Health Informatics Policy, National Institute of Public Health, Wako, Japan (K.H.); Department of Hygiene, Kitasato University School of Medicine, Sagamihara, Japan (K.H.); and Chugoku Rosai Hospital Research Center for the Promotion of Health and Employment Support, Japan Organization of Occupational Health and Safety, Hiroshima, Japan (A.T.).

Journal of Occupational and Environmental Medicine
|April 14, 2026
PubMed
Summary

Occupation is linked to cancer risk in Japan, with manual and transport jobs showing higher risks, especially for men. Professional roles may have lower cancer incidence, varying by cancer type and sex.

Keywords:
Japancancer riskcase–control studydetection biasoccupation

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