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The Nose-Lung Axis in Chronic Obstructive Pulmonary Disease: An Emerging Interface for Clinical Endotyping, Biomarker
Pasquale Ambrosino1, Giuseppina Marcuccio2, Claudio Candia2
1Istituti Clinici Scientifici Maugeri IRCCS, Scientific Directorate of Telese Terme Institute, 82037 Telese Terme, Italy.
Abstract:
Chronic obstructive pulmonary disease (COPD) continues to be framed predominantly as a disorder of the lower airways, defined operationally by airflow limitation, and assessed through a combination of spirometry, symptom burden, and exacerbation history [...].
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