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Impact of 3D Virtual Modeling on Perioperative Outcomes in Robot-Assisted Partial Nephrectomy
Francesco Passaro1, Achille Aveta1, Gianluca Spena1
1Department of Urology, National Cancer Institute IRCCS G. Pascale Foundation, 80131 Naples, Italy.
Diagnostics (Basel, Switzerland)
|April 14, 2026
Summary
Robot-assisted partial nephrectomy (RAPN) outcomes improved with 3D virtual models. Preoperative planning and navigation using patient-specific 3D reconstructions enhanced trifecta achievement, reducing positive surgical margins in RAPN procedures.
Area of Science:
- Urology
- Surgical Technology
- Medical Imaging
Background:
- Robot-assisted partial nephrectomy (RAPN) is a complex procedure with inherent risks.
- Perioperative complications and achieving optimal functional and oncologic outcomes remain challenges.
Purpose of the Study:
- To evaluate the impact of patient-specific 3D virtual model reconstructions on perioperative outcomes in RAPN.
- To assess if 3D modeling improves trifecta achievement, defined by negative margins, preserved renal function, and absence of complications.
Main Methods:
- A comparative study of 307 patients undergoing RAPN for renal tumors.
- Analysis of 69 patients using 3D modeling (Medics3D) versus 238 patients in a 2D imaging control group.
- Outcomes assessed included trifecta achievement, surgical margins, estimated glomerular filtration rate (eGFR) preservation, and complication rates.
Main Results:
- The 3D modeling group demonstrated a significantly lower rate of positive surgical margins (5% vs. 15%, p=0.030).
- Trifecta achievement was significantly higher in the 3D group (51% vs. 32%, p=0.004).
- 3D modeling was identified as an independent predictor of trifecta achievement (OR 2.1, p=0.013).
Conclusions:
- Patient-specific 3D kidney reconstructions significantly improve perioperative outcomes in RAPN.
- Integration of 3D modeling into surgical workflows can enhance precision and optimize patient results.
- 3D modeling supports better surgical planning and execution for complex partial nephrectomies.

