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Artificial Intelligence in Ocular Surface Tumors: Current Advances, Challenges, and Future Directions
Hamidreza Ghanbari1, Nikoo Bayan2, Shakiba Rahimi2
1Eye Research Center, Farabi Eye Hospital, Tehran 1336616351, Iran.
Diagnostics (Basel, Switzerland)
|April 14, 2026
Summary
Artificial intelligence (AI) offers promising advancements for diagnosing rare ocular surface tumors (OSTs). This review explores AI applications, challenges, and future directions to improve patient management in ophthalmology.
Area of Science:
- Ophthalmology
- Oncology
- Medical Imaging
- Artificial Intelligence
Background:
- Ocular surface tumors (OSTs) are rare, potentially life-threatening neoplasms.
- Accurate diagnosis relies on expert interpretation and advanced imaging, with excisional biopsy as the gold standard.
- Current diagnostic limitations highlight the need for less invasive, accessible methods.
Purpose of the Study:
- To provide a comprehensive review of artificial intelligence (AI) advancements in the management of ocular surface tumors (OSTs).
- To examine the current state and future potential of AI in diagnosing and managing OSTs.
Main Methods:
- Review of AI models applied to ophthalmic tumors using imaging data.
- Classification of AI diagnostic tools based on imaging modalities and OST types.
- Discussion of challenges and future directions for AI implementation in clinical ophthalmology.
Main Results:
- AI demonstrates significant promise in enhancing OST diagnosis and patient management.
- AI models are being developed using various imaging modalities for specific OSTs.
- Key challenges include data limitations and ethical considerations.
Conclusions:
- AI holds substantial potential to improve OST diagnosis and management, bridging technological innovation with clinical needs.
- Further research and development are crucial for integrating AI into routine clinical ophthalmology practice.
- AI can ultimately lead to improved patient outcomes for challenging OST conditions.

