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Conventional Repetitive Transcranial Magnetic Stimulation for Depression: A Step-by-Step Protocol
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Lived Experiences and Engagement in an Exercise Program for People with Resistant Major Depression: TRACE-RMD Study
José Etxaniz-Oses1,2, Mikel Tous-Espelosin1,2, Pedro Sánchez3,4
1Gizartea, Kirola eta Ariketa Fisikoa Ikerkuntza Taldea (GIKAFIT), Society, Sports, and Physical Exercise Research Group, Department of Physical Education and Sport, Faculty of Education and Sport, Physical Activity and Sport Sciences Section, University of the Basque Country (UPV/EHU), 01007 Vitoria-Gasteiz, Spain.
Healthcare (Basel, Switzerland)
|April 14, 2026
Summary
Engagement in exercise for resistant major depression (RMD) depends on personal, social, and environmental factors. Understanding these lived experiences is key to designing effective, long-term physical activity interventions for RMD.
Area of Science:
- Psychiatry
- Exercise Science
- Behavioral Medicine
Background:
- Resistant major depression (RMD) involves persistent symptoms despite treatment, causing significant impairment.
- Physical activity interventions show promise for RMD, but engagement factors are unclear.
Purpose of the Study:
- To explore lived experiences of participants in a supervised exercise program for RMD.
- To identify factors influencing engagement with physical activity interventions for RMD.
Main Methods:
- The study used purposive sampling and thematic analysis.
- A socioecological framework guided the exploration of participant experiences.
- Semi-structured interviews were conducted after a 12-week exercise program.
Main Results:
- Engagement was influenced by intrapersonal (symptoms, expectations), interpersonal (social support), and environmental (program logistics) factors.
- Motivation stemmed from emotional, physical, and social goals.
- Barriers included fatigue, anhedonia, and medication side effects.
Conclusions:
- Exercise intervention engagement in RMD is multifactorial, involving personal, social, and environmental interactions.
- Understanding lived experiences is crucial for developing person-centered, sustainable interventions.
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