Sustainable Remediation of Pharmaceuticals Using Crop-Residue-Derived Carbons: Bridging Multi-Component Adsorption...

This work is devoted to the synthesis and comprehensive study of activated carbons (ACs) obtained from agricultural wastes-specifically corn cob (C) and onion (O)-for the effective removal of paracetamol (PCM) and sulfamethoxazole (SMX) from aqueous media. The synthesis was carried out by chemical activation using H₃PO₄, HNO₃, and NaOH as activating agents, which made it possible to obtain materials with a clearly defined microporous structure (microporous fraction V_micro/V_total = 0.75-0.81) and specific surface chemistry. Particular attention was paid to studying the kinetics and equilibrium of adsorption in both single-component and binary (two-pollutant) systems. It was established that the equilibrium time is 8 h, and the experimental data are best described by a pseudo-second-order kinetic model. During binary adsorption tests, the competitive behavior was observed for certain materials, such as the corn-derived carbon activated with HNO₃ (AC-CN) and the onion-derived carbon activated with HNO₃ (AC-ON), where molecules compete for active sites. Conversely, synergistic effects were identified in other systems, controlled by specific surface-functional groups and hydration effects. The maximum adsorption capacity was found to be 29.4 mg∙g^-1 for PCM on the AC-CN sample. Adsorption mechanisms, including multilayer isotherm profiles and the competition between pollutant and water molecules, were interpreted using quantum chemical calculations within the framework of Density Functional Theory (DFT). These calculations revealed that partial deprotonation and intense solvation of SMX molecules at natural pH reduce their adsorption capacity. In contrast, the PCM structure favors π-π interactions and the formation of strong hydrogen bonds with oxygen-containing groups on the carbon surface. These results demonstrate the high potential of using agro-industrial waste to create a new generation of selective adsorbents with tailored surface properties.