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Transoral Endoscopic Thyroidectomy Vestibular Approach for Thyroid Lobectomy
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Association Between Cervical Drainage and Early Post-Thyroidectomy Outcomes: A Systematic Review and Meta-Analysis.
Michael Kostares1,2, Evangelos Kostares3,4, Maria Kakazani2
1Department of Anatomy, National and Kapodistrian University of Athens, 106 79 Athens, Greece.
Journal of Clinical Medicine
|April 14, 2026
Summary
Routine cervical drainage after thyroidectomy does not reduce bleeding complications but increases surgical site infections and hospital stays. This systematic review suggests avoiding routine drains for better patient recovery.
Area of Science:
- Surgical Oncology
- Endocrine Surgery
- Evidence-Based Medicine
Background:
- Traditional use of cervical drains post-thyroidectomy aimed to prevent fluid collection and bleeding.
- Advancements in surgical techniques and care pathways prompt re-evaluation of routine drain use, especially for short-stay and outpatient procedures.
Purpose of the Study:
- To conduct a systematic review and meta-analysis evaluating the association between postoperative cervical drainage and outcomes following thyroidectomy.
Main Methods:
- Systematic literature search of PubMed/MEDLINE, Google Scholar, Semantic Scholar, and Cochrane Central Register of Controlled Trials (2005-2026).
- Inclusion of randomized controlled trials and non-randomized comparative studies on adult thyroidectomy patients.
- Meta-analysis of outcomes including cervical hematoma, surgical site infection (SSI), seroma, bleeding, reoperation, and length of hospital stay.
Main Results:
- Thirty studies (2810 patients) were analyzed.
- Cervical drainage showed no significant association with reduced cervical hematoma, seroma, postoperative bleeding, or reoperation.
- Drain use was linked to a significantly higher risk of surgical site infection (SSI) and a longer hospital stay (1.96 days).
Conclusions:
- Routine cervical drainage after thyroidectomy does not offer benefits in preventing bleeding complications.
- Drainage is associated with adverse outcomes, including increased SSI risk and prolonged hospitalization.
- Findings suggest that routine cervical drainage may not be advantageous and could lead to less favorable recovery.
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