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Related Concept Videos

Endocarditis IV: Nursing Management01:29

Endocarditis IV: Nursing Management

605
Infective endocarditis (IE) is a chronic infection of the heart's endocardium, primarily affecting the heart valves. A detailed nursing assessment for a patient with IE involves collecting subjective and objective data to ensure an accurate diagnosis and timely intervention.Subjective DataThe nurse gathers information about the patient's symptoms and complaints during the subjective assessment. Patients with infective endocarditis often report non-specific symptoms that can mimic other...
605
Endocarditis III: Medical Management01:18

Endocarditis III: Medical Management

347
Infective endocarditis management involves a multifaceted approach encompassing infection prevention, lifestyle modifications, pharmacological therapy, and surgical management.Infection Prevention:Hand Hygiene: Thorough handwashing is crucial to prevent the spread of infection. Hand hygiene should be performed regularly, especially before and after using the restroom.Oral Hygiene: Good oral hygiene is essential. It includes brushing teeth immediately after waking up and before bed, flossing...
347
Endocarditis II: Clinical Features of Infective Endocarditis01:25

Endocarditis II: Clinical Features of Infective Endocarditis

861
Endocarditis can present various clinical features depending on the causative organism and the patient's underlying health conditions. Initially, the clinical features of infective endocarditis develop gradually, presenting with nonspecific symptoms that can be easily mistaken for other illnesses.General SymptomsEarly symptoms of infective endocarditis are fever, chills, weakness, malaise, fatigue, and weight loss. These symptoms reflect the systemic nature of the infection and the body's...
861
Endocarditis I: Introduction01:25

Endocarditis I: Introduction

833
Introduction:Endocarditis is the infection of the endocardium, the inner lining of the heart and its valves. When the heart muscle is involved, the condition is termed myocarditis, while an infection of the outer lining is called pericarditis. Infective endocarditis (IE) primarily affects the endocardium, where pathogens adhere to the valves or lining, forming vegetation that can lead to severe complications. Infective endocarditis occurs when microorganisms, usually bacteria from other body...
833

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Prognostic Value of HALP Score for In-Hospital Mortality in Patients with Infective Endocarditis.

Emirhan Hancıoğlu1, Sevgi Özcan2, Sevil Tuğrul Yavuz3

  • 1Department of Cardiology, Istanbul Medipol University, Acıbadem Medipol District Hospital, Acıbadem, Şht. Emin Çölen Sokağı No:18, 34718 Kadıkoy, Turkey.

Journal of Clinical Medicine
|April 14, 2026
PubMed
Summary

The hemoglobin-albumin-lymphate-platelet (HALP) score can help predict in-hospital mortality in infective endocarditis (IE) patients. A low HALP score indicates a higher risk of death and more severe disease.

Keywords:
HALP scoreinfective endocarditismortality

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Area of Science:

  • Cardiology
  • Internal Medicine
  • Critical Care Medicine

Background:

  • Infective endocarditis (IE) presents significant morbidity and mortality risks.
  • Early risk stratification for IE patients is crucial for improved outcomes.
  • The prognostic value of the hemoglobin-albumin-lymphocyte-platelet (HALP) score in IE is not well-established.

Purpose of the Study:

  • To evaluate the prognostic value of the HALP score in patients hospitalized with IE.
  • To determine if the HALP score can predict in-hospital and 1-year mortality in IE patients.

Main Methods:

  • A retrospective cohort study of 218 adult IE patients from January 2016 to January 2025.
  • HALP score calculated from admission laboratory values.
  • Receiver operating characteristic (ROC) analysis and Cox regression identified predictors of mortality.

Main Results:

  • In-hospital mortality was 38.5%.
  • Lower HALP scores were significantly associated with increased in-hospital mortality (AUC 0.784, cut-off 15.1).
  • Low HALP scores correlated with severe complications and higher mortality rates (in-hospital and 1-year).

Conclusions:

  • The HALP score is an independent predictor of in-hospital mortality in IE.
  • It effectively identifies IE patients with more severe disease and poorer prognosis.
  • The HALP score offers a simple, complementary tool for risk stratification and clinical decision-making in IE.