Related Experiment Video
Updated: Jun 8, 2026

10:28
Imaging Mismatch Repair and Cellular Responses to DNA Damage in Bacillus subtilis
Published on: February 9, 2010
Correction: Smolarz et al. Radiation-Induced Bystander Effect Mediated by Exosomes Involves the Replication Stress in
Mateusz Smolarz1, Łukasz Skoczylas1, Marta Gawin1
1Maria Skłodowska-Curie National Research Institute of Oncology, 44-102 Gliwice, Poland.
International Journal of Molecular Sciences
|April 14, 2026
Abstract:
In the original publication [...].
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Related Concept Videos
Mismatch Repair
Overview
DNA Damage can Stall the Cell Cycle
In response to DNA damage, cells can pause the cell cycle to assess and repair the breaks. However, the cell must check the DNA at certain critical stages during the cell cycle. If the cell cycle pauses before DNA replication, the cells will contain twice the amount of DNA. On the other hand, if cells arrest after DNA replication but before mitosis, they will contain four times the normal amount of DNA. With a host of specialized proteins at their disposal,cells must use the right protein at...
Mismatch Repair
Organisms are capable of detecting and fixing nucleotide mismatches that occur during DNA replication. This sophisticated process requires identifying the new strand and replacing the erroneous bases with correct nucleotides. Mismatch repair is coordinated by many proteins in both prokaryotes and eukaryotes.
The Mutator Protein Family Plays a Key Role in DNA Mismatch Repair
The human genome has more than 3 billion base pairs of DNA per cell. Prior to cell division, that vast amount of genetic...
The Mutator Protein Family Plays a Key Role in DNA Mismatch Repair
The human genome has more than 3 billion base pairs of DNA per cell. Prior to cell division, that vast amount of genetic...