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Correction: Smolarz et al. Radiation-Induced Bystander Effect Mediated by Exosomes Involves the Replication Stress in

Mateusz Smolarz1, Łukasz Skoczylas1, Marta Gawin1

  • 1Maria Skłodowska-Curie National Research Institute of Oncology, 44-102 Gliwice, Poland.

International Journal of Molecular Sciences
|April 14, 2026
PubMed

Abstract:

In the original publication [...].

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Mismatch Repair01:36

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DNA Damage can Stall the Cell Cycle

In response to DNA damage, cells can pause the cell cycle to assess and repair the breaks. However, the cell must check the DNA at certain critical stages during the cell cycle. If the cell cycle pauses before DNA replication, the cells will contain twice the amount of DNA. On the other hand, if cells arrest after DNA replication but before mitosis, they will contain four times the normal amount of DNA. With a host of specialized proteins at their disposal,cells must use the right protein at...
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Organisms are capable of detecting and fixing nucleotide mismatches that occur during DNA replication. This sophisticated process requires identifying the new strand and replacing the erroneous bases with correct nucleotides. Mismatch repair is coordinated by many proteins in both prokaryotes and eukaryotes.
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