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Updated: Apr 15, 2026

Production and Testing of Antimicrobial Peptides and Their Mimics
Published on: April 10, 2026
Artificial intelligence drives the identification and screening of novel antibiotics and antimicrobial peptides
Qi Zhou1,2, Lei Sun1,2, Yanhong Ou1,2
1National Reference Laboratory of Veterinary Drug Residues (HZAU), Huazhong Agricultural University, 1 Shizishan Street, Hongshan District, Wuhan, Hubei 430070, China.
Abstract:
The discovery of new antimicrobial drugs has become urgent due to the growing threat of antimicrobial resistance in the 21st century. However, high-throughput screening is costly and time-consuming. Artificial intelligence (AI) can facilitate the discovery of novel antibiotics and antimicrobial peptides (AMPs) by accelerating identification and reducing development costs. This review focuses on the application of artificial intelligence in the discovery of novel antibiotics and AMPs, highlighting recent advances and practical strategies in AI-driven antibacterial drug development. Ultimately, this article aims to provide practical support and guidance for researchers in antimicrobial discovery, thereby contributing to resolving the global health crisis.
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