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Related Concept Videos

Rous Sarcoma Virus (RSV) and Cancer01:03

Rous Sarcoma Virus (RSV) and Cancer

Rous Sarcoma virus or RSV was discovered by F. Peyton Rous in the year 1911 as a filterable transmissible agent that could cause tumors in chickens. He won a Nobel Prize for this discovery in 1966. His experiments clearly demonstrated that some cancers could be caused by infectious agents and led to the discovery of many more cancer-causing viruses in animals as well as humans.
RSV is a retrovirus that contains two copies of a plus-strand  RNA genome. Its genome consists of four main open...
Rous Sarcoma Virus (RSV) and Cancer01:03

Rous Sarcoma Virus (RSV) and Cancer

Rous Sarcoma virus or RSV was discovered by F. Peyton Rous in the year 1911 as a filterable transmissible agent that could cause tumors in chickens. He won a Nobel Prize for this discovery in 1966. His experiments clearly demonstrated that some cancers could be caused by infectious agents and led to the discovery of many more cancer-causing viruses in animals as well as humans.
RSV is a retrovirus that contains two copies of a plus-strand  RNA genome. Its genome consists of four main open...
Acute Respiratory Failure-II01:21

Acute Respiratory Failure-II

Type I Respiratory Failure, or hypoxemic respiratory failure, occurs when the partial pressure of oxygen (PaO2) in arterial blood falls below 60 mmHg while breathing room air without a corresponding increase in arterial carbon dioxide levels (PaCO2). This condition highlights a significant impairment in the lungs' capacity to oxygenate the blood.
The underlying physiological abnormalities that contribute to hypoxemic respiratory failure include:
Acute Respiratory Failure-V01:29

Acute Respiratory Failure-V

The treatment for acute respiratory failure varies based on factors like the underlying cause, overall health, and severity. A collaborative healthcare team is essential for early detection, often through arterial blood gas analysis. Identifying the cause is the primary goal, with treatment strategies adjusted for ventilation/perfusion (V/Q) mismatch, shunting, or diffusion impairment.
Ensure that patients are monitored continuously for their response to therapy, including changes in...
Bias in Epidemiological Studies01:29

Bias in Epidemiological Studies

Biases can arise at various stages of research, from study design and data collection to analysis and interpretation. Recognizing and addressing these biases is essential to ensure the validity and reliability of epidemiological findings.Broadly speaking, biases in epidemiology fall into three main categories: selection bias, information bias, and confounding. A more detailed description of possible biases is:
Respiratory Syncytial Virus Disease01:29

Respiratory Syncytial Virus Disease

Human respiratory syncytial virus (RSV) is a widespread pathogen that primarily targets infants and young children but also poses a serious health risk to elderly and immunocompromised individuals. Belonging to the Pneumoviridae family, RSV is a negative-sense, single-stranded RNA virus within the Pneumovirus genus. Its global health burden is significant, with millions of cases annually resulting in hospitalizations and mortality, particularly in resource-limited settings. Although most...

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Related Experiment Video

Updated: Jul 4, 2026

An In vitro Model to Study Immune Responses of Human Peripheral Blood Mononuclear Cells to Human Respiratory Syncytial Virus Infection
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Disparities in Admissions for RSV: A Retrospective Observational Study.

Catherine G Coughlin1,2, Michael C Monuteaux1,2, Zhe Zhang3

  • 1Division of Emergency Medicine, Boston Children's Hospital.

Pediatric Emergency Care
|April 14, 2026
PubMed
Summary

Black and multiracial children with RSV bronchiolitis had lower admission rates, while non-English speakers faced higher ICU admission odds. These disparities highlight the need for equitable care in pediatric respiratory syncytial virus management.

Keywords:
RSVadmissionbronchiolitisdisparities

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Area of Science:

  • Pediatrics
  • Public Health
  • Health Equity

Background:

  • Respiratory syncytial virus (RSV) is a leading cause of pediatric hospitalizations.
  • Understanding disparities in RSV care is crucial for improving outcomes in young children.

Purpose of the Study:

  • To investigate if race, ethnicity, and preferred language influence hospitalization and ICU admission for children with RSV bronchiolitis.
  • To adjust for disease severity and demographic factors in analyzing these disparities.

Main Methods:

  • Observational study of children under 2 diagnosed with RSV in an urban pediatric emergency department (2020-2024).
  • Multivariable logistic regression analysis to assess the association between race, ethnicity, language, and hospitalization/ICU admission.
  • Controlled for clinical covariates like tachypnea, hypoxia, and viral coinfections.

Main Results:

  • 33.8% of 2948 children diagnosed with RSV were admitted.
  • Black and multiracial children had significantly lower odds of hospital admission compared to White children.
  • Children speaking Spanish or other non-English languages had increased odds of ICU admission.

Conclusions:

  • Significant racial and linguistic disparities exist in RSV hospitalization and ICU admission rates.
  • Further research is needed to identify clinical and structural factors contributing to these inequities.
  • Addressing these disparities is essential for advancing equitable care for children with RSV.