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An In vitro Model to Study Immune Responses of Human Peripheral Blood Mononuclear Cells to Human Respiratory Syncytial Virus Infection
Published on: December 10, 2013
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Disparities in Admissions for RSV: A Retrospective Observational Study
Catherine G Coughlin1,2, Michael C Monuteaux1,2, Zhe Zhang3
1Division of Emergency Medicine, Boston Children's Hospital.
Pediatric Emergency Care
|April 14, 2026
Summary
Black and multiracial children with RSV bronchiolitis had lower admission rates, while non-English speakers faced higher ICU admission odds. These disparities highlight the need for equitable care in pediatric respiratory syncytial virus management.
Area of Science:
- Pediatrics
- Public Health
- Health Equity
Background:
- Respiratory syncytial virus (RSV) is a leading cause of pediatric hospitalizations.
- Understanding disparities in RSV care is crucial for improving outcomes in young children.
Purpose of the Study:
- To investigate if race, ethnicity, and preferred language influence hospitalization and ICU admission for children with RSV bronchiolitis.
- To adjust for disease severity and demographic factors in analyzing these disparities.
Main Methods:
- Observational study of children under 2 diagnosed with RSV in an urban pediatric emergency department (2020-2024).
- Multivariable logistic regression analysis to assess the association between race, ethnicity, language, and hospitalization/ICU admission.
- Controlled for clinical covariates like tachypnea, hypoxia, and viral coinfections.
Main Results:
- 33.8% of 2948 children diagnosed with RSV were admitted.
- Black and multiracial children had significantly lower odds of hospital admission compared to White children.
- Children speaking Spanish or other non-English languages had increased odds of ICU admission.
Conclusions:
- Significant racial and linguistic disparities exist in RSV hospitalization and ICU admission rates.
- Further research is needed to identify clinical and structural factors contributing to these inequities.
- Addressing these disparities is essential for advancing equitable care for children with RSV.
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