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[Prevention of delayed cardiogenic shock in 850 patients with myocardial infarction (author's transl)]

V Rosival, K Prónay

    Zeitschrift Fur Kardiologie
    |January 1, 1979
    PubMed

    Insights

    Early detection of decreased cardiac output using respiratory alkalosis in acute myocardial infarction patients can prevent cardiogenic shock. This intervention significantly reduced hospital mortality rates.

    Area of Science:

    • Cardiology
    • Critical Care Medicine

    Context:

    • Acute myocardial infarction (AMI) patients often experience decreased cardiac output.
    • Respiratory alkalosis is an indicator of reduced cardiac output.

    Purpose:

    • To investigate the efficacy of monitoring cardiac output via acid-base balance in AMI patients.
    • To evaluate the impact of early intervention with cardiac glycosides in patients with low cardiac output.

    Summary:

    • Cardiac output was monitored daily in 850 AMI patients using acid-base balance determinations.
    • In 84 patients with low cardiac output, cardiac glycosides were administered, resulting in only 1 death from cardiogenic shock and 3 from heart failure.
    • In the remaining 766 patients, only 1 died from heart failure.

    Impact:

    • The intervention successfully prevented delayed cardiogenic shock and heart failure.
    • Overall hospital lethality decreased to 11.06% compared to 21.70% in historical literature data.
    • This approach demonstrates a significant reduction in mortality for acute myocardial infarction patients.

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