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PsychiatryBench: a multi-task benchmark for LLMs in psychiatry.

Aya E Fouda1, Abdelrahman A Hassan1, Radwa J Hanafy1,2

  • 1Compumacy for Artificial Intelligence Solutions, Cairo, Egypt.

NPJ Digital Medicine
|April 14, 2026
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Summary

PsychiatryBench, a new benchmark for large language models (LLMs), uses expert-validated psychiatric texts for evaluation. It reveals LLMs struggle with clinical consistency and safety in complex mental health tasks.

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Area of Science:

  • Artificial Intelligence in Medicine
  • Psychiatric Diagnostics and Treatment

Background:

  • Large language models (LLMs) show promise for psychiatric practice, aiding diagnosis, documentation, and therapy.
  • Current LLM evaluations use limited data, lacking clinical validity and failing to assess complex diagnostic reasoning.

Purpose of the Study:

  • Introduce PsychiatryBench, a novel benchmark for evaluating LLMs in psychiatry.
  • Ensure rigorous evaluation using expert-validated psychiatric textbooks and casebooks.

Main Methods:

  • Developed PsychiatryBench with 5,188 expert-annotated items across eleven psychiatric QA tasks.
  • Evaluated frontier LLMs (e.g., Gemini, GPT-5) and medical models (e.g., MedGemma) using standard metrics and LLM-as-judge.
  • Tasks included diagnostic reasoning, treatment planning, and longitudinal follow-up.

Main Results:

  • Identified significant gaps in LLM clinical consistency and safety, especially in multi-turn follow-up and management.
  • Frontier LLMs and medical models showed limitations in complex psychiatric reasoning.
  • PsychiatryBench provides a comprehensive assessment of LLM capabilities in mental health.

Conclusions:

  • Current LLMs require specialized tuning and improved evaluation for safe and effective psychiatric applications.
  • PsychiatryBench serves as a critical tool for advancing AI in mental healthcare.
  • The benchmark highlights the need for robust evaluation paradigms beyond simple Q&A.