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PsychiatryBench: a multi-task benchmark for LLMs in psychiatry.
Aya E Fouda1, Abdelrahman A Hassan1, Radwa J Hanafy1,2
1Compumacy for Artificial Intelligence Solutions, Cairo, Egypt.
NPJ Digital Medicine
|April 14, 2026
Summary
PsychiatryBench, a new benchmark for large language models (LLMs), uses expert-validated psychiatric texts for evaluation. It reveals LLMs struggle with clinical consistency and safety in complex mental health tasks.
Area of Science:
- Artificial Intelligence in Medicine
- Psychiatric Diagnostics and Treatment
Background:
- Large language models (LLMs) show promise for psychiatric practice, aiding diagnosis, documentation, and therapy.
- Current LLM evaluations use limited data, lacking clinical validity and failing to assess complex diagnostic reasoning.
Purpose of the Study:
- Introduce PsychiatryBench, a novel benchmark for evaluating LLMs in psychiatry.
- Ensure rigorous evaluation using expert-validated psychiatric textbooks and casebooks.
Main Methods:
- Developed PsychiatryBench with 5,188 expert-annotated items across eleven psychiatric QA tasks.
- Evaluated frontier LLMs (e.g., Gemini, GPT-5) and medical models (e.g., MedGemma) using standard metrics and LLM-as-judge.
- Tasks included diagnostic reasoning, treatment planning, and longitudinal follow-up.
Main Results:
- Identified significant gaps in LLM clinical consistency and safety, especially in multi-turn follow-up and management.
- Frontier LLMs and medical models showed limitations in complex psychiatric reasoning.
- PsychiatryBench provides a comprehensive assessment of LLM capabilities in mental health.
Conclusions:
- Current LLMs require specialized tuning and improved evaluation for safe and effective psychiatric applications.
- PsychiatryBench serves as a critical tool for advancing AI in mental healthcare.
- The benchmark highlights the need for robust evaluation paradigms beyond simple Q&A.

