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Updated: Apr 16, 2026

Facile Preparation of 2Z,4E-Dienamides by the Olefination of Electron-deficient Alkenes with Allyl Acetate
Published on: June 21, 2017
Hyperconjugation-Driven Ester Migration Enabled Aerobic 1,3-Iodohydroxylation with Iodoform: A Triple
Hong Hou1, Linyang Jiang1, Mengyan Gao1
1School of Chemistry & Chemical Engineering, Yangzhou University, Yangzhou 225009, China.
Abstract:
We report herein a visible-light-mediated aerobic 1,3-iodohydroxylation of allyl carboxylates using iodoform as an iodine source. This cascade reaction is initiated by the homolytic cleavage of the carbon-iodine bond in iodoform under visible light irradiation, generating an iodine radical, and triggers a cascade reaction of radical addition, ester migration, and hydroxylation. This practical trifunctionalization protocol features mild conditions and broad functional group tolerance.
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