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A Study of Intradialytic Complications in Chronic Kidney Disease Patients

Basavaraj Nilugal1, Siddanagouda M Biradar1, Sandeep Patil1

  • 1General Medicine, Shri BM Patil Medical College, Hospital and Research Centre, BLDE (Deemed to be University), Vijayapura, IND.

Cureus
|April 15, 2026
PubMed

Insights

Intradialytic complications, particularly hypotension, affected one-third of hemodialysis sessions. High ultrafiltration rates and interdialytic weight gain were linked to these hypotensive events in chronic kidney disease patients.

Area of Science:

  • Nephrology
  • Internal Medicine
  • Critical Care Medicine

Background:

  • Chronic kidney disease (CKD) poses a global health challenge, necessitating renal replacement therapy.
  • Hemodialysis is a vital treatment but is associated with intradialytic complications impacting patient safety and treatment efficacy.

Purpose of the Study:

  • To determine the incidence and patterns of intradialytic complications in CKD patients undergoing hemodialysis.
  • To identify clinical factors associated with the occurrence of these complications.

Main Methods:

  • An observational cross-sectional study involving 90 CKD patients and 205 hemodialysis sessions.
  • Prospective observation of intradialytic complications, with monitoring of blood pressure and clinical parameters.
  • Data analysis using IBM SPSS Statistics, version 26.

Main Results:

  • A significant proportion of sessions (33.2%) experienced complications.
  • Intradialytic hypotension was the most frequent complication (20.4%), followed by hypertension (23.5% of complicated sessions).
  • Hypotension was associated with higher ultrafiltration goals, higher rates, elevated pre-dialysis systolic blood pressure, and greater interdialytic weight gain.

Conclusions:

  • Intradialytic complications are common, with hypotension being the most prevalent.
  • Higher ultrafiltration rates and increased interdialytic weight gain are risk factors for hypotension.
  • Optimizing fluid management and monitoring hemodynamics are crucial for patient safety during hemodialysis.
Abstract

Keywords:
chronic kidney diseasehemodialysishypotensionintradialytic complicationsultrafiltration

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