Ocular Biometric Correlations in a Mexican Population: Implications for Intraocular Lens Planning in Anterior Segment...

To describe the distribution and correlations of ocular biometric parameters in a Mexican population and to assess the differences across axial-length groups.

This is a retrospective, multicentrical, cross-sectional study of healthy eyes examined with IOL Master 700® from 2018 to 2020. Patients were classified into four axial length (AL) groups: short (≤22 mm), normal (>22 mm to <24.50 mm), long (≥24.50 mm to <27.5 mm), and extremely long (≥27.5 mm). Main biometric variables included AL, anterior chamber depth (ACD), lens thickness (LT), central corneal thickness (CCT), corneal diameter (white-to-white [WTW]), pupil diameter, average keratometry (K), and μ-chord.

The study included 1622 eyes with a mean age of 57 years. Mean biometric values were AL 23.61 mm, ACD 3.21 mm, LT 4.32 mm, CCT 542 μm, WTW 12 mm, K 43.66 D, and μ-chord 0.40 mm. AL group distribution was short 5.9%, normal 67.2%, long 21.8%, and extremely long 5.1%. Strong correlations were observed between age and LT (r = 0.65, P < 0.001), ACD and LT (r = 0.64, P < 0.001), and AL and ACD (r = 0.50, P < 0.001). μ-chord values decreased progressively as AL increased, showing statistically significant differences among AL groups.

Biometric parameters varied systematically across AL categories in a large Mexican cohort. LT increased with age and inversely correlated with ACD, whereas AL correlated positively with ACD and negatively with keratometry. These findings have direct implications for intraocular lens power calculation and risk assessment in cataract and refractive surgery.