Mechanisms of drug-enzyme interactions

Uridine phosphorylase association with vimentin. Intracellular distribution and localization.

The Journal of biological chemistry·2001

Genomic structure, chromosomal mapping, and promoter region analysis of murine uridine phosphorylase gene.

Cancer research·1999

beta-alanine and alpha-fluoro-beta-alanine concentrative transport in rat hepatocytes is mediated by GABA transporter GAT-2.

The American journal of physiology·1999

Expression, characterization, and detection of human uridine phosphorylase and identification of variant uridine phosphorolytic activity in selected human tumors.

Cancer research·1998

Discrete roles of hepatocytes and nonparenchymal cells in uridine catabolism as a component of its homeostasis.

The American journal of physiology·1998

Phase I clinical and pharmacological studies of benzylacyclouridine, a uridine phosphorylase inhibitor.

Clinical cancer research : an official journal of the American Association for Cancer Research·1998

Hypotension Prediction Index versus Mean Arterial Pressure Alarm for Preventing Intraoperative Hypotension in Elective Non-Cardiac Surgery: A Randomized Controlled Trial.

Anesthesiology·2026

A National Delphi Study to Inform Modernization of Anesthesiology Residency Case Log Requirements.

Anesthesiology·2026

Hypotension Prediction Index versus High Mean Arterial Pressure Target for Preventing Intraoperative Hypotension: A Randomized Controlled Trial.

Anesthesiology·2026

Tidal swing of endotracheal tube cuff pressure as a measurement of inspiratory effort and lung stress during pressure support ventilation: a proof-of-concept study.

Anesthesiology·2026

Preoperative Glucagon-Like Peptide-1 Receptor Agonists and Postoperative Outcomes: An Observational Analysis.

Anesthesiology·2026

Frequency of adherence to obstetric anesthesia best practices for cesarean delivery: A multicenter retrospective cohort analysis.

Anesthesiology·2026

AI Structural Biology in Nephrology: Powerful Scaffolds, Fragile Certainties.

Journal of the American Society of Nephrology : JASN·2026

Design, synthesis, and preliminary antiproliferative evaluation of azetidine-functionalized pyrrolo[2,3-d]pyrimidines with integrated computational studies.

Journal of biomolecular structure & dynamics·2026

Vibrational Circular Dichroism Spectra of 2,5-Diaminoterephtalate Macrocycles Reveal Distant Vibrational Exciton Coupling.

Chemistry (Weinheim an der Bergstrasse, Germany)·2026

Bayesian Optimization of a Suzuki Coupling for the Industrial Synthesis of a Sartan Drug Intermediate.

ACS omega·2026

Reversible Coordination Modes in Piperazine-Based Ru(II)-p-Cymene Acylthiourea Complexes: Modulating DNA Groove Binding for Selective Antimelanoma Activity.

ChemMedChem·2026

AI-enabled discovery and biochemical optimization of minibinders targeting cancer cell-surface proteins.

Nature communications·2026

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Uridine phosphorylase association with vimentin. Intracellular distribution and localization.

Genomic structure, chromosomal mapping, and promoter region analysis of murine uridine phosphorylase gene.

beta-alanine and alpha-fluoro-beta-alanine concentrative transport in rat hepatocytes is mediated by GABA transporter GAT-2.

Expression, characterization, and detection of human uridine phosphorylase and identification of variant uridine phosphorolytic activity in selected human tumors.

Discrete roles of hepatocytes and nonparenchymal cells in uridine catabolism as a component of its homeostasis.

Phase I clinical and pharmacological studies of benzylacyclouridine, a uridine phosphorylase inhibitor.

Hypotension Prediction Index versus Mean Arterial Pressure Alarm for Preventing Intraoperative Hypotension in Elective Non-Cardiac Surgery: A Randomized Controlled Trial.

A National Delphi Study to Inform Modernization of Anesthesiology Residency Case Log Requirements.

Hypotension Prediction Index versus High Mean Arterial Pressure Target for Preventing Intraoperative Hypotension: A Randomized Controlled Trial.

Tidal swing of endotracheal tube cuff pressure as a measurement of inspiratory effort and lung stress during pressure support ventilation: a proof-of-concept study.

Preoperative Glucagon-Like Peptide-1 Receptor Agonists and Postoperative Outcomes: An Observational Analysis.

Frequency of adherence to obstetric anesthesia best practices for cesarean delivery: A multicenter retrospective cohort analysis.

AI Structural Biology in Nephrology: Powerful Scaffolds, Fragile Certainties.

Design, synthesis, and preliminary antiproliferative evaluation of azetidine-functionalized pyrrolo[2,3-d]pyrimidines with integrated computational studies.

Vibrational Circular Dichroism Spectra of 2,5-Diaminoterephtalate Macrocycles Reveal Distant Vibrational Exciton Coupling.

Bayesian Optimization of a Suzuki Coupling for the Industrial Synthesis of a Sartan Drug Intermediate.

Reversible Coordination Modes in Piperazine-Based Ru(II)-p-Cymene Acylthiourea Complexes: Modulating DNA Groove Binding for Selective Antimelanoma Activity.

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