Topical Chlorhexidine-Induced Oral Allergic Reaction: A Case Report

Area of Science:

• Dentistry
• Allergology
• Pharmacology

Background:

• Topical chlorhexidine is commonly used in dentistry for its antimicrobial properties.
• Adverse reactions, though rare, can occur with topical medications.
• Upper lip swelling can stem from various causes, necessitating accurate diagnosis.

Purpose of the Study:

• To report a rare case of allergic reaction to topical chlorhexidine gel.
• To highlight the importance of differential diagnosis in cases of upper lip swelling.
• To emphasize appropriate therapeutic management for such reactions.

Main Methods:

• Case report detailing a patient's presentation with upper lip swelling.
• Clinical examination and exclusion of infectious etiology.
• Pharmacological intervention with prednisone.

Main Results:

• The patient experienced significant upper lip swelling hours after applying chlorhexidine gel.
• Infective causes originating from maxillary incisors were ruled out.
• Prednisone administration resulted in rapid resolution of the swelling.

Conclusions:

• Topical chlorhexidine gel can induce rare allergic reactions presenting as localized swelling.
• Accurate differential diagnosis is crucial for managing upper lip swelling in dental patients.
• Prompt and appropriate treatment, such as corticosteroids, can effectively manage allergic reactions.