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Published on: July 3, 2013
Licorice-Induced Pseudoaldosteronism Caused by Rikkunshito in an Extremely Low Birth Weight Infant
Toshihiro Nakayama1, Naofumi Hanyu1, Shonosuke Nara1
1Department of Pediatrics and Adolescent Medicine, Tokyo Medical University, Tokyo, Japan.
Abstract:
We report an extremely low birth weight infant with gastroesophageal reflux disease who developed persistent hypokalemia and metabolic alkalosis after treatment with rikkunshito. These findings gradually resolved after discontinuation of rikkunshito and potassium supplementation, suggesting licorice-induced pseudoaldosteronism.
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The PCT is the initial segment of the renal tubule, extending from the Bowman's capsule that encloses the glomerulus. Its convoluted structure and microvilli-lined cells increase the surface area for reabsorption. The PCT reabsorbs glucose, amino acids, sodium, and water from the filtrate, ensuring essential...

