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Hem-O-Lock Clip to Replace Stapler for Laparoscopic Appendectomy Provides Value-Based Care
Angel Guan1,2, Aldin Malkoc1,2, Ashley Wang1,2
1Department of General Surgery, Arrowhead Regional Medical Center, Colton, CA, USA.
The American Surgeon
|April 15, 2026
Summary
Hem-O-Lok clips (HOL) offer a cost-effective alternative to endoscopic staplers for laparoscopic appendectomy (LA). This study found no significant difference in patient outcomes or complications, supporting HOL clips for stump closure in LA.
Area of Science:
- Surgical Innovation
- Cost-Effectiveness in Healthcare
Background:
- Laparoscopic appendectomy (LA) is the standard treatment for acute appendicitis.
- Stump closure methods, such as Hem-O-Lok clips (HOL) and endoscopic staplers (ES), vary in cost.
- Evaluating cost-saving strategies without compromising patient outcomes is crucial in healthcare.
Purpose of the Study:
- To compare the cost-effectiveness of Hem-O-Lok clips (HOL) versus endoscopic staplers (ES) for stump closure during laparoscopic appendectomy (LA).
- To evaluate if HOL clips can provide cost savings without negatively impacting patient outcomes.
Main Methods:
- Retrospective case-control study of 571 patients undergoing LA from 2016-2022.
- Patients were divided into groups based on stump closure: HOL clips (n=341) or ES (n=230).
- Propensity score matching (1:1) created 177 pairs, controlling for age, sex, BMI, and ASA classification.
- Outcomes assessed included 30-day complications, length of stay, estimated blood loss (EBL), and readmission rates.
Main Results:
- The HOL group had patients who were older, had more comorbidities, higher BMI, and higher ASA classifications.
- Despite demographic and comorbidity differences, no increased post-operative complication rates were observed between HOL and ES groups.
- Return to hospital rates were similar: 5.3% for HOL vs. 7.9% for ES.
- Cost analysis revealed HOL clips ($32 for a six-pack) are significantly cheaper than ES ($273 per load).
Conclusions:
- Hem-O-Lok clips are a safe and effective alternative for stump closure in laparoscopic appendectomy.
- Utilizing HOL clips demonstrates no increase in patient morbidity compared to endoscopic staplers.
- HOL clips represent a substantial cost-saving opportunity for healthcare systems performing LA.

