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Related Concept Videos

Clinical Trials01:16

Clinical Trials

11.2K
Clinical trials are prospective experimental studies conducted on humans to determine the safety and efficacy of treatments, drugs, diet methods, and medical devices. Using statistics in clinical trials enables researchers to derive reasonable and accurate conclusions from the collected data, allowing them to make wise decisions in uncertain situations. In medical research, statistical methods are crucial for preventing errors and bias.
There are four phases in a clinical trial. A phase one...
11.2K
Clinical Trials: Overview01:11

Clinical Trials: Overview

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Clinical development focuses on how the drug will interact with the human body and encompasses four key phases of clinical trials, each serving a specific purpose in assessing the safety and effectiveness of new drugs. These phases overlap and build upon one another. Phase I involves a small group of healthy volunteers (typically 20-80 individuals) or, in cases where significant toxicity is expected, patients with the targeted disease, such as cancer or AIDS. The volunteers are tested for...
5.5K
Blinding01:11

Blinding

4.1K
Blinding is a commonly used method of not telling participants which treatment a subject is receiving. Blinding is a critical part of a randomized control trial or RCT. It reduces the bias that affects the results. In an RCT, blinding is used in the form of a placebo. A placebo effect occurs when untreated subjects falsely believe they have received the treatment and report improved symptoms. A placebo or a dummy treatment is administered to subjects to negate the bias caused by such an effect.
4.1K
Transmission-based Precautions I: Contact, Enteric, and Droplets01:17

Transmission-based Precautions I: Contact, Enteric, and Droplets

5.1K
Transmission-based precautions are for patients known to be infected or suspected to be infected or colonized with organisms that pose a significant risk to others. Some transmission-based precautions include contact, enteric, and droplet.
Contact Precautions:
Contact precautions are the measures taken to prevent the transmission of infectious agents, especially epidemiologically important microorganisms such as MRSA or influenza, primarily transmitted through direct or indirect contact with an...
5.1K
Contact-dependent Signaling01:19

Contact-dependent Signaling

48.9K
Contact-dependent signaling, as the name suggests, requires that communicating cells be in direct contact with each other. This is achieved either through receptor-ligand interactions or by specialized cytoplasmic channels that allow the flow of small molecules between cells. In animal cells, channels called gap junctions facilitate contact-dependent signaling in certain tissues, whereas, plasmodesmata perform a similar function in plants.
Gap Junctions
In animal cells, gap junctions are formed...
48.9K

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Measurement of ethnicity in clinical trials: Delphi survey and consensus statement.

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Deescalation, Discontinuation, and Deimplementation Trials: Evaluating Whether and How to Do Less.

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Protocol for a SPIRIT extension for reporting pragmatic and explanatory trial protocols designed using the PRECIS tool (SPIRIT-PRECIS).

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SPIRIT 2025 statement: updated guideline for protocols of randomised trials.

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Related Experiment Video

Updated: Apr 16, 2026

Author Spotlight: Enhancing Engineering Education via WebVR-Based Online Laboratories
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Author Spotlight: Enhancing Engineering Education via WebVR-Based Online Laboratories

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Virtual and Remotely Conducted Trials: Connection Without Contact

Alison J Huang1,2, Gregory M Marcus2,3, An-Wen Chan4,5

  • 1Editor-in-Chief, JAMA+ Trials.

JAMA
|April 15, 2026
PubMed
Summary

No abstract available in PubMed .

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