Related Experiment Video
Updated: Jun 12, 2026

Color Spot Test As a Presumptive Tool for the Rapid Detection of Synthetic Cathinones
Published on: February 5, 2018
Occupational exposures to illicit drugs in forensic science divisions
Jennie Cox1, Jacob Bartels1, Mamadou Niang2
1Division of Field Studies and Engineering, Field Research Branch, National Institute for Occupational Safety and Health, Cincinnati, Ohio.
Forensic lab workers may be exposed to illicit drugs like fentanyl. Fentanyl exposure limits were exceeded in air and on surfaces at multiple sites, indicating a need for enhanced safety protocols.
Area of Science:
- Occupational Health
- Forensic Science
- Toxicology
Background:
- Forensic scientists handle diverse illicit substances daily.
- Concerns exist regarding occupational exposure to opioids like fentanyl and other drugs.
- The National Institute for Occupational Safety and Health (NIOSH) initiated an exposure assessment.
Purpose of the Study:
- To assess occupational exposure risks for forensic laboratory personnel.
- To evaluate exposure to fentanyl, cocaine, heroin, and methamphetamine.
- To compare measured exposure levels with established occupational exposure limits.
Main Methods:
- Collected and analyzed personal and area air samples.
- Collected and analyzed handwipe and surface wipe samples.
- Collected and analyzed personal urine samples for drug metabolites.
- Compared results to American Conference of Governmental Industrial Hygienists (ACGIH) Threshold Limit Values (TLVs).
Main Results:
- Fentanyl exposure limits (100 ng/m³) were exceeded in personal air samples at 4 of 11 sites.
- Fentanyl surface limits (10 ng/cm²) were exceeded on commonly touched surfaces at 3 of 11 sites.
- Detectable levels of cocaine and methamphetamine were found in air and surface samples.
- Illicit drug metabolites were detected in urine samples from personnel at 8 of 11 sites.
Conclusions:
- Occupational safety thresholds for fentanyl were exceeded in forensic laboratories.
- Established safety thresholds are lacking for other illicit drugs like methamphetamine and cocaine.
- Prudent occupational safety requires minimizing chronic low-dose exposure due to unknown health effects.
- Further research is needed to understand potential health effects of chronic low-dose illicit drug exposure.
Related Concept Videos
Enhanced Elimination of Poison
Antidotes serve a crucial role in counteracting the effects of poison by inhibiting enzymes responsible for producing harmful drug metabolites. In some cases, these toxic metabolites can be neutralized by endogenous cosubstrates, which are maintained at specific concentrations to prevent interaction with cellular macromolecules and subsequent cell death.
Renal excretion is the...
Drug Abuse and Addiction: Pharmacological Phenomena
Drug Concentrations: Measurements
Plasma —...
Drug Excretion: Pulmonary and Glandular Routes
Drugs can also be excreted in breast milk, which is crucial for breastfeeding infants. The process...
Drug Excretion: Miscellaneous Routes
Pharmaceutical Poisoning: Potential Scenarios

