Single-stage Penile Resurfacing for Foreign Body Granuloma: A Simplified Negative Pressure Wound Therapy-assisted
Daihun Kang1, Seung Eun Hong1, Youn Hwan Kim2
1College of Medicine, Ewha Womans University, Seoul, Republic of Korea; Department of Plastic and Reconstructive Surgery, Ewha Womans University Seoul Hospital, Seoul, Republic of Korea.
Objective:
To present a simplified single-stage protocol using negative pressure wound therapy (NPWT) combined with dermal substitute and split-thickness skin graft (STSG) for penile foreign body granuloma resulting from subcutaneous injection of various substances.
Methods:
A retrospective review was conducted on 11 consecutive patients who underwent penile resurfacing for foreign body granuloma between March 2018 and June 2025. All patients received complete excision of granulomatous tissue, Matriderm Flex application, STSG, and NPWT (-125 mmHg). Primary outcomes included graft take rate, complications, hospital stay, and patient satisfaction assessed by a 9-item questionnaire.
Results:
Median patient age was 55.0 years (IQR: 51.5-58.0). Foreign body types included Vaseline alone (n = 6), Vaseline with hyaluronic acid (n = 1), hyaluronic acid alone (n = 1), and unknown fillers (n = 3). The first dressing change was performed on postoperative day 5 with near-complete graft take achieved in 10 of 11 cases (90.9%). Complications included partial graft loss with hematoma requiring evacuation (n = 1) and chronic discharge from remnant filler material (n = 1). Median satisfaction score was 37.0/45 (IQR: 36.5-39.0). Median follow-up was 18.0 months (IQR: 12.0-24.0).
Conclusion:
NPWT-assisted single-stage reconstruction using dermal substitute and STSG provides a simple, reliable, and reproducible option for penile foreign body granuloma, avoiding complex flap surgery while achieving excellent graft take and high patient satisfaction.


