Personalised management of community-acquired pneumonia and the role of Clinical Decision Support Software
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Multiplex Therapeutic Drug Monitoring by Isotope-dilution HPLC-MS/MS of Antibiotics in Critical Illnesses
Published on: August 30, 2018
Christopher Hatton1,2, Catherine Atkin3, Suzy Gallier3,4
1Department of Inflammation and Ageing, School of Infection, Inflammation, and Immunology, College of Medicine and Health, University of Birmingham, Birmingham, UK c.hatton@bham.ac.uk.
Abstract:
Community-acquired pneumonia (CAP) is one of the most common causes of hospital admission and is associated with significant morbidity and mortality. National and international guidelines are available to guide the management of CAP, including antibiotic prescribing. However, these guidelines are often not adhered to and there is significant overprescribing of broad-spectrum antibiotics, contributing to the growing pandemic of antimicrobial resistance. Clinical Decision Support Software (CDSS) are electronic tools that use individual patient data to generate patient specific assessments or recommendations, that can then be acted on by the patient or clinical decision maker. This article reviews the evidence surrounding the initial management of CAP in hospital and considers the potential of CDSS to support CAP management.
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