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Published on: January 19, 2019
Neural circuits in lung adenocarcinoma modulate immunosurveillance
Kostas A Papavassiliou1, Dimitrios J Stravopodis2, Athanasios G Papavassiliou3
1First University Department of Respiratory Medicine, 'Sotiria' Chest Hospital, Medical School, National and Kapodistrian University of Athens, Athens 11527, Greece.
None:
Recent evidence from a study published in Nature by Wei et al. reveals a bidirectional tumor-brain axis in lung cancer that suppresses immune surveillance by reprogramming macrophages and disabling T cell responses. These findings highlight neuroimmune signaling as a key regulator of cancer progression and a promising therapeutic target.
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