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Related Experiment Video

Updated: Apr 17, 2026

Author Spotlight: Improving Radiation Therapy Access with Radiation Planning Assistant
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An optimisation framework for resource allocation in palliative and end-of-life care.

Elizabeth Williams1,2, Syaribah Brice3,4, Daniel Gartner3,5,6

  • 1School of Mathematics, Cardiff University, Cardiff, CF24 4AG, UK. Elizabeth.Williams22@wales.nhs.uk.

Scientific Reports
|April 15, 2026
PubMed
Summary

This study introduces an optimization framework for planning end-of-life care for frail elderly patients. It balances cost efficiency with patient-centered outcomes, improving healthcare coordination and resource allocation.

Keywords:
Data-driven modellingHealthcare optimisationPalliative careResource planning

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Area of Science:

  • Health Services Research
  • Operations Research
  • Geriatric Medicine

Background:

  • End-of-life care for frail elderly patients often involves high healthcare use, fragmented services, and poor coordination, leading to variable quality and increased costs.
  • Existing planning approaches rarely integrate patient-level care pathways into operational models that balance efficiency with patient-centered outcomes.

Purpose of the Study:

  • To present a proof-of-concept optimization framework for strategic resource planning in end-of-life care for frail, elderly, and palliative patients.
  • To illustrate the framework's application using synthetic data for anticipatory planning and service configuration comparison.

Main Methods:

  • Developed two optimization model formulations: one minimizing cost, the other aligning demand with capacity.
  • Stratified patients into ten categories with varying resource needs across hospital beds, palliative beds, community nursing, and virtual wards.
  • Utilized a synthetic dataset of twelve-month service trajectories to assess model performance.

Main Results:

  • Both optimization models yielded feasible resource allocations that met expected demand within capacity limits.
  • Patient groups were generally assigned to consistent pathways, with some shifts based on the optimization objective, highlighting cost-efficiency vs. utilization trade-offs.
  • Demand increased in the final months of life but was manageable under the planning assumptions.

Conclusions:

  • The modeling framework demonstrates the feasibility of using optimization for anticipatory planning in end-of-life care.
  • This approach supports more coordinated, efficient, and patient-centered care by enabling comparisons of different service configurations.