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Optimization of pulmonary blood flow analysis method using dynamic chest radiography.

Tasuku Nakajima1,2, Ryuichi Ushijima3, Rie Tanaka4

  • 1Department of Radiology, Toyama University Hospital, Toyama, Toyama, Japan.

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Summary

Optimizing region of interest (ROI) placement in dynamic chest radiography (DCR) improves pulmonary blood flow analysis. Specific upper and inside heart locations yield higher signal values for diagnosing chronic thromboembolic pulmonary hypertension.

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chronic thromboembolic pulmonary hypertensiondynamic chest radiographyflat panel detectorpulmonary blood flow analysis

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Area of Science:

  • Medical Imaging
  • Cardiovascular Imaging
  • Pulmonary Hypertension Research

Background:

  • Dynamic chest radiography (DCR) is used for pulmonary blood flow analysis.
  • Pixel values in a left ventricle region of interest (ROI) serve as reference signals.
  • The impact of ROI placement on analysis accuracy remains unclear.

Purpose of the Study:

  • To determine optimal ROI locations for clinically useful DCR images with enhanced signal values.
  • To improve the accuracy of pulmonary blood flow analysis using DCR.

Main Methods:

  • Analysis of 40 DCR, SPECT, CTA, and angiography datasets from 15 patients with chronic thromboembolic pulmonary hypertension.
  • Calculation of the time difference rate of each peak value (PD%) based on reference signals and heart rate phase.
  • Categorization and statistical comparison of PD% values for high- and low-signal ROIs, with visual inspection using CTA.

Main Results:

  • Significant differences in PD% were observed when ROIs were placed in upper and inside heart regions on DCR (p < 0.05).
  • Low-signal ROIs on CTA were typically located centrally, involving the right ventricle and excluding the left ventricular cavity.

Conclusions:

  • Identified specific ROIs yielding higher signal values in DCR for pulmonary blood flow analysis.
  • Findings are expected to enhance the efficiency and reliability of DCR imaging for diagnosing chronic thromboembolic pulmonary hypertension.