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Author Spotlight: Enhancing Graft Viability Assessment Through Quantitative Metrics and Innovative Reservoir Systems
Published on: August 2, 2024
Association of Lipid Core Burden Index With Early Progression of Cardiac Allograft Vasculopathy in Patients After
Kenta Otsuka1, Sakae Takenaka1, Toshiyuki Nagai1
1Department of Cardiovascular Medicine, Faculty of Medicine and Graduate School of Medicine, Hokkaido University.
Background:
The association of the lipid-core burden index (LCBI), measured using near-infrared spectroscopy-intravascular ultrasound (NIRS-IVUS), with early progression of cardiac allograft vasculopathy remains unclear.
Methods And Results:
We prospectively examined 12 consecutive heart transplant recipients who underwent NIRS-IVUS and IVUS. Patients were stratified according to the median maximum LCBI in a 4-mm segment (maxLCBI4 mm) of 223 at 1 month. The magnitude of maximal intimal thickness (MIT) progression was greater in the higher maxLCBI4 mmgroup.
Conclusions:
Patients with a higher maxLCBI4 mmat baseline exhibited greater MIT progression during the first post-transplant year.
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