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Translating behavioral interventions into virtual reality: the Transcend Framework for immersive health design
Rosalba Hernandez1, Killivalavan Solai2, Soonhyung Kwon3
1School of Social Work, University of Illinois at Urbana-Champaign, Urbana, IL, United States.
Frontiers in Digital Health
|April 16, 2026
Summary
The Transcend Framework offers a systematic process for adapting behavioral interventions into virtual reality (VR) platforms. This methodology ensures effective and accessible digital health tools for diverse clinical applications.
Area of Science:
- Digital Health
- Immersive Technologies
- Behavioral Science
Background:
- Virtual Reality (VR) is transitioning from entertainment to a key tool in clinical and public health.
- VR applications in medicine include pain management, rehabilitation, and cognitive training, with potential for chronic disease management.
- Adapting evidence-based behavioral interventions for VR requires a structured approach.
Purpose of the Study:
- To introduce the Transcend Framework, a systematic model for translating behavioral interventions into VR.
- To provide a reproducible process for developing VR-based health interventions for research and clinical use.
- To illustrate the framework's application with Joviality™, a VR intervention for hemodialysis patients.
Main Methods:
- The Transcend Framework consists of five stages: population identification, VR curriculum adaptation, pre-production planning, previsualization and asset creation, and iterative VR development and testing.
- Emphasis on user-centered design, considering physical limitations, cognitive load, and accessibility.
- Incorporation of interactive, visually rich, modular, and gamified environments with culturally attuned content.
Main Results:
- The framework facilitates the development of usable, accessible, and engaging VR interventions.
- Interactive and gamified elements enhance learning and skill acquisition.
- Data-informed refinement ensures sustained user engagement and intervention effectiveness.
Conclusions:
- The Transcend Framework offers a practical roadmap for creating and optimizing VR-based behavioral health interventions.
- Immersive technology can significantly advance health education and promote behavior change.
- This approach enables scalable and equitable implementation of digital health solutions across clinical settings.

